increased fibroblast apoptosis_Fntb<tm1.1Mbrg>/Fntb<tm1.1Mbrg>,Pggt1b<tm1Mbrg>/Pggt1b<tm1Mbrg>

http://metadb.riken.jp/0013501I129P2OlaHsdC57BL6Fntbtm11MbrgFntbtm11MbrgPggt1btm1MbrgPggt1btm1MbrgPggt1btm1MbrgFntbtm11Mbrg

increased fibroblast apoptosis_Fntb<tm1.1Mbrg>/Fntb<tm1.1Mbrg>,Pggt1b<tm1Mbrg>/Pggt1b<tm1Mbrg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein geranylgeranyltransferase type I, beta subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:1917514
• farnesyltransferase, CAAX box, beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1861305

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fntb<tm1.1Mbrg>/Fntb<tm1.1Mbrg>,Pggt1b<tm1Mbrg>/Pggt1b<tm1Mbrg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pggt1b<tm1Mbrg>|Fntb<tm1.1Mbrg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased fibroblast apoptosis
  http://purl.obolibrary.org/obo/MP_0013501

文献

http://purl.org/net/cito/citesAsAuthority

• Meng. Liu, et.al., Targeting the protein prenyltransferases efficiently reduces tumor development in mice with K-RAS-induced lung cancer., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20308544