increased embryonic tissue cell apoptosis_Mdm2<tm1Glo>/Mdm2<+>,Mdm4<tm1Glo>/Mdm4<+>

http://metadb.riken.jp/0013504I129S6SvEvTac129S7SvEvBrdC57BL6Mdm2tm1GloMdm2Mdm4tm1GloMdm4Mdm2Mdm4tm1GloMdm4Mdm2tm1Glo

increased embryonic tissue cell apoptosis_Mdm2<tm1Glo>/Mdm2<+>,Mdm4<tm1Glo>/Mdm4<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformed mouse 3T3 cell double minute 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:107934
• transformed mouse 3T3 cell double minute 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96952

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mdm2<tm1Glo>/Mdm2<+>,Mdm4<tm1Glo>/Mdm4<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mdm2<+>|Mdm4<tm1Glo>|Mdm4<+>|Mdm2<tm1Glo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased embryonic tissue cell apoptosis
  http://purl.obolibrary.org/obo/MP_0013504

文献

http://purl.org/net/cito/citesAsAuthority

• Tamara. Terzian, et.al., Haploinsufficiency of Mdm2 and Mdm4 in tumorigenesis and development., Molecular and cellular biology, 2007, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17526734