increased endoplasmic reticulum stress_Gt(ROSA)26Sor<tm1(CAG-cas9*,-EGFP)Fezh>/?,Tmem258<tm1.1(KOMP)Vlcg>/Tmem258<+>

http://metadb.riken.jp/0020354IC57BL6NTacGtROSA26Sortm1CAGcas9EGFPFezhTmem258tm11KOMPVlcgTmem258Tmem258tm11KOMPVlcgTmem258GtROSA26Sortm1CAGcas9EGFPFezh

increased endoplasmic reticulum stress_Gt(ROSA)26Sor<tm1(CAG-cas9*,-EGFP)Fezh>/?,Tmem258<tm1.1(KOMP)Vlcg>/Tmem258<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transmembrane protein 258
  http://metadb.riken.jp/db/mgi_rdf/MGI:1916288
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(CAG-cas9*,-EGFP)Fezh>/?,Tmem258<tm1.1(KOMP)Vlcg>/Tmem258<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tmem258<tm1.1(KOMP)Vlcg>|Tmem258<+>|Gt(ROSA)26Sor<tm1(CAG-cas9*,-EGFP)Fezh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6NTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• http://purl.obolibrary.org/obo/MP_0020354

文献

http://purl.org/net/cito/citesAsAuthority

• Daniel B. Graham, et.al., TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation., Cell reports, 2016, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/27974209