F. Ruberti, et.al., Phenotypic knockout of nerve growth factor in adult transgenic mice reveals severe deficits in basal forebrain cholinergic neurons, cell death in the spleen, and skeletal muscle dystrophy., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/10729339

F. Ruberti, et.al., Phenotypic knockout of nerve growth factor in adult transgenic mice reveals severe deficits in basal forebrain cholinergic neurons, cell death in the spleen, and skeletal muscle dystrophy., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, 20

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(CMV-IgkvaD11)ACat
  http://metadb.riken.jp/db/mgi_rdf/MGI:2429312
• Tg(CMV-IgkvaD11)BCat
  http://metadb.riken.jp/db/mgi_rdf/MGI:3721910
• Tg(CMV-IghvaD11)DCat
  http://metadb.riken.jp/db/mgi_rdf/MGI:3721909
• Tg(CMV-IghvaD11)CCat
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447027

class

http://purl.org/net/cito/citesAsAuthority

• Tg(CMV-IgkvaD11)ACat
  http://metadb.riken.jp/db/mgi_rdf/MGI:2429312
• Tg(CMV-IgkvaD11)BCat
  http://metadb.riken.jp/db/mgi_rdf/MGI:3721910
• Tg(CMV-IghvaD11)DCat
  http://metadb.riken.jp/db/mgi_rdf/MGI:3721909
• Tg(CMV-IghvaD11)CCat
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447027

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal limb posture_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0004263IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• scoliosis_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0000161IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• increased splenocyte apoptosis_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0009322IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• amyloidosis_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0000604IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• abnormal hippocampal mossy fiber morphology_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0002761IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• abnormal gait_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0001406IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• abnormal splenic cell ratio_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0008826IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• delayed hair appearance_Tg(CMV-IghvaD11)CCat/Tg(CMV-IghvaD11)CCat,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0000422IC57BL6SJLTgCMVIghvaD11CCatTgCMVIghvaD11CCatTgCMVIgkvaD11BCat0TgCMVIgkvaD11BCatTgCMVIghvaD11CCat
• abnormal cholinergic neuron morphology_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0001038IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• abnormal splenic cell ratio_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0008826IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• abnormal skeletal muscle fiber morphology_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0003084IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• decreased skeletal muscle fiber diameter_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0009402IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• small superior cervical ganglion_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0001015IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• prenatal lethality, complete penetrance_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0011091IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11DCatTgCMVIgkvaD11BCat
• abnormal superior cervical ganglion morphology_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0001011IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• abnormal spatial working memory_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0008428IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• decreased body weight_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0001262IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• impaired coordination_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0001405IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• abnormal lumbar dorsal root ganglion morphology_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0006404IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• premature death_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)ACat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0002083IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11ACat0TgCMVIgkvaD11BCat0TgCMVIgkvaD11ACatTgCMVIgkvaD11BCatTgCMVIghvaD11CCat
• abnormal spatial working memory_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0008428IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• increased splenocyte apoptosis_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0009322IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• decreased body weight_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0001262IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• abnormal skeletal muscle fiber morphology_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0003084IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• decreased skeletal muscle fiber diameter_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0009402IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• decreased skeletal muscle mass_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0004819IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• abnormal spatial learning_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0001463IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• abnormal sympathetic system morphology_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0001007IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• decreased body weight_Tg(CMV-IghvaD11)CCat/Tg(CMV-IghvaD11)CCat,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0001262IC57BL6SJLTgCMVIghvaD11CCatTgCMVIghvaD11CCatTgCMVIgkvaD11BCat0TgCMVIgkvaD11BCatTgCMVIghvaD11CCat
• postnatal lethality_Tg(CMV-IghvaD11)CCat/Tg(CMV-IghvaD11)CCat,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0002082IC57BL6SJLTgCMVIghvaD11CCatTgCMVIghvaD11CCatTgCMVIgkvaD11BCat0TgCMVIgkvaD11BCatTgCMVIghvaD11CCat
• amyloidosis_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0000604IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• abnormal spatial learning_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0001463IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• abnormal superior cervical ganglion morphology_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0001011IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• abnormal limb posture_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0004263IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• abnormal sympathetic system morphology_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0001007IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• increased thermal nociceptive threshold_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0001973IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• increased neuron apoptosis_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0003203IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• increased thermal nociceptive threshold_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0001973IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• decreased skeletal muscle mass_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0004819IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• impaired coordination_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0001405IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• small superior cervical ganglion_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0001015IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• abnormal long term spatial reference memory_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0008432IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• delayed eyelid opening_Tg(CMV-IghvaD11)CCat/Tg(CMV-IghvaD11)CCat,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0001290IC57BL6SJLTgCMVIghvaD11CCatTgCMVIghvaD11CCatTgCMVIgkvaD11BCat0TgCMVIgkvaD11BCatTgCMVIghvaD11CCat
• abnormal lumbar dorsal root ganglion morphology_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0006404IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• scoliosis_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0000161IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• increased neuron apoptosis_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0003203IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• abnormal gait_Tg(CMV-IghvaD11)CCat/0,Tg(CMV-IgkvaD11)BCat/0
  http://metadb.riken.jp/0001406IC57BL6SJLTgCMVIghvaD11CCat0TgCMVIgkvaD11BCat0TgCMVIghvaD11CCatTgCMVIgkvaD11BCat
• abnormal hippocampal mossy fiber morphology_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0002761IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• abnormal long term spatial reference memory_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0008432IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat
• abnormal cholinergic neuron morphology_Tg(CMV-IghvaD11)DCat/0,Tg(CMV-IgkvaD11)ACat/0
  http://metadb.riken.jp/0001038IC57BL6SJLTgCMVIghvaD11DCat0TgCMVIgkvaD11ACat0TgCMVIghvaD11DCatTgCMVIgkvaD11ACat