T. Frugier, et.al., Nuclear targeting defect of SMN lacking the C-terminus in a mouse model of spinal muscular atrophy., Human molecular genetics, 2000, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/10749994

T. Frugier, et.al., Nuclear targeting defect of SMN lacking the C-terminus in a mouse model of spinal muscular atrophy., Human molecular genetics, 2000, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Eno2-cre)39Jme
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177175
• Smn1<tm1Jme>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384151
• Smn1<tm1.1Jme>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384155

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Eno2-cre)39Jme
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177175
• Smn1<tm1Jme>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384151
• Smn1<tm1.1Jme>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2384155

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal skeletal muscle fiber morphology_Smn1<tm1Jme>/Smn1<tm1.1Jme>,Tg(Eno2-cre)39Jme/0
  http://metadb.riken.jp/0003084I129C57BL6SJLSmn1tm1JmeSmn1tm11JmeTgEno2cre39Jme0Smn1tm1JmeTgEno2cre39JmeSmn1tm11Jme
• abnormal motor neuron innervation pattern_Smn1<tm1Jme>/Smn1<tm1.1Jme>,Tg(Eno2-cre)39Jme/0
  http://metadb.riken.jp/0000940I129C57BL6SJLSmn1tm1JmeSmn1tm11JmeTgEno2cre39Jme0Smn1tm1JmeTgEno2cre39JmeSmn1tm11Jme
• embryonic lethality, complete penetrance_Smn1<tm1.1Jme>/Smn1<tm1.1Jme>
  http://metadb.riken.jp/0011092I129C57BL6SJLSmn1tm11JmeSmn1tm11JmeSmn1tm11Jme
• impaired righting response_Smn1<tm1Jme>/Smn1<tm1.1Jme>,Tg(Eno2-cre)39Jme/0
  http://metadb.riken.jp/0001523I129C57BL6SJLSmn1tm1JmeSmn1tm11JmeTgEno2cre39Jme0Smn1tm1JmeTgEno2cre39JmeSmn1tm11Jme
• hypotonia_Smn1<tm1Jme>/Smn1<tm1.1Jme>,Tg(Eno2-cre)39Jme/0
  http://metadb.riken.jp/0004144I129C57BL6SJLSmn1tm1JmeSmn1tm11JmeTgEno2cre39Jme0Smn1tm1JmeTgEno2cre39JmeSmn1tm11Jme
• tremors_Smn1<tm1Jme>/Smn1<tm1.1Jme>,Tg(Eno2-cre)39Jme/0
  http://metadb.riken.jp/0000745I129C57BL6SJLSmn1tm1JmeSmn1tm11JmeTgEno2cre39Jme0Smn1tm1JmeTgEno2cre39JmeSmn1tm11Jme
• abnormal motor neuron morphology_Smn1<tm1Jme>/Smn1<tm1.1Jme>,Tg(Eno2-cre)39Jme/0
  http://metadb.riken.jp/0000937I129C57BL6SJLSmn1tm1JmeSmn1tm11JmeTgEno2cre39Jme0Smn1tm1JmeTgEno2cre39JmeSmn1tm11Jme
• no abnormal phenotype detected_Smn1<tm1.1Jme>/Smn1<+>
  http://metadb.riken.jp/0002169I129C57BL6SJLSmn1tm11JmeSmn1Smn1Smn1tm11Jme
• premature death_Smn1<tm1Jme>/Smn1<tm1.1Jme>,Tg(Eno2-cre)39Jme/0
  http://metadb.riken.jp/0002083I129C57BL6SJLSmn1tm1JmeSmn1tm11JmeTgEno2cre39Jme0Smn1tm1JmeTgEno2cre39JmeSmn1tm11Jme
• no abnormal phenotype detected_Smn1<tm1Jme>/Smn1<tm1Jme>
  http://metadb.riken.jp/0002169I129C57BL6JSmn1tm1JmeSmn1tm1JmeSmn1tm1Jme
• abnormal motor capabilities/coordination/movement_Smn1<tm1Jme>/Smn1<tm1.1Jme>,Tg(Eno2-cre)39Jme/0
  http://metadb.riken.jp/0002066I129C57BL6SJLSmn1tm1JmeSmn1tm11JmeTgEno2cre39Jme0Smn1tm1JmeTgEno2cre39JmeSmn1tm11Jme
• abnormal limb posture_Smn1<tm1Jme>/Smn1<tm1.1Jme>,Tg(Eno2-cre)39Jme/0
  http://metadb.riken.jp/0004263I129C57BL6SJLSmn1tm1JmeSmn1tm11JmeTgEno2cre39Jme0Smn1tm1JmeTgEno2cre39JmeSmn1tm11Jme