Veerle. Compernolle, et.al., Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice., Nature medicine, 2002, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/12053176

Veerle. Compernolle, et.al., Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice., Nature medicine, 2002, 8

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal lung development_Vegfa<tm2Pec>/Vegfa<tm2Pec>
  http://metadb.riken.jp/0001176I129S1Sv129X1SvJVegfatm2PecVegfatm2PecVegfatm2Pec
• atelectasis_Vegfa<tm1Pec>/Vegfa<tm1Pec>
  http://metadb.riken.jp/0001177I129S1Sv129X1SvJVegfatm1PecVegfatm1PecVegfatm1Pec
• abnormal pulmonary alveolus epithelial cell morphology_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0002273I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• abnormal alveolar lamellar body morphology_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0010813I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• respiratory distress_Vegfa<tm1Pec>/Vegfa<tm1Pec>
  http://metadb.riken.jp/0001954I129S1Sv129X1SvJVegfatm1PecVegfatm1PecVegfatm1Pec
• respiratory distress_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0001954I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• cyanosis_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0001575I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• no abnormal phenotype detected_Vegfa<tm3.1Pec>/Vegfa<tm3.1Pec>
  http://metadb.riken.jp/0002169I129S1Sv129X1SvJVegfatm31PecVegfatm31PecVegfatm31Pec
• abnormal angiogenesis_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0000260I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• neonatal lethality, complete penetrance_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0011087I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• abnormal lung vasculature morphology_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0004007I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• respiratory failure_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0001953I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• abnormal lung development_Vegfa<tm1Pec>/Vegfa<tm1Pec>
  http://metadb.riken.jp/0001176I129S1Sv129X1SvJVegfatm1PecVegfatm1PecVegfatm1Pec
• thick pulmonary interalveolar septum_Vegfa<tm2Pec>/Vegfa<tm2Pec>
  http://metadb.riken.jp/0001179I129S1Sv129X1SvJVegfatm2PecVegfatm2PecVegfatm2Pec
• decreased type II pneumocyte number_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0010811I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• abnormal surfactant secretion_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0004780I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• embryonic lethality during organogenesis, incomplete penetrance_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0011108I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• thick pulmonary interalveolar septum_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0001179I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• atelectasis_Vegfa<tm2Pec>/Vegfa<tm2Pec>
  http://metadb.riken.jp/0001177I129S1Sv129X1SvJVegfatm2PecVegfatm2PecVegfatm2Pec
• atelectasis_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0001177I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• abnormal lung development_Epas1<tm1Pec>/Epas1<tm1Pec>
  http://metadb.riken.jp/0001176I129SvSwissEpas1tm1PecEpas1tm1PecEpas1tm1Pec
• thick pulmonary interalveolar septum_Vegfa<tm1Pec>/Vegfa<tm1Pec>
  http://metadb.riken.jp/0001179I129S1Sv129X1SvJVegfatm1PecVegfatm1PecVegfatm1Pec