Craig H. Bassing, et.al., Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors., Cell, 2003, 114

http://rdf.ncbi.nlm.nih.gov/pubmed/12914700

Craig H. Bassing, et.al., Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors., Cell, 2003, 114

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• H2afx<tm1Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2670743

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased B cell derived lymphoma incidence_H2afx<tm1Fwa>/H2afx<+>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002023I129S6SvEvTac129S7SvEvBrdC57BL6H2afxtm1FwaH2afxTrp53tm1BrdTrp53tm1BrdH2afxTrp53tm1BrdH2afxtm1Fwa
• increased T cell derived lymphoma incidence_H2afx<tm1Fwa>/H2afx<tm1Fwa>
  http://metadb.riken.jp/0002024I129S6SvEvTacH2afxtm1FwaH2afxtm1FwaH2afxtm1Fwa
• premature death_H2afx<tm1Fwa>/H2afx<+>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002083I129S6SvEvTac129S7SvEvBrdC57BL6H2afxtm1FwaH2afxTrp53tm1BrdTrp53tm1BrdH2afxTrp53tm1BrdH2afxtm1Fwa
• increased teratoma incidence_H2afx<tm1Fwa>/H2afx<+>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002627I129S6SvEvTac129S7SvEvBrdC57BL6H2afxtm1FwaH2afxTrp53tm1BrdTrp53tm1BrdH2afxTrp53tm1BrdH2afxtm1Fwa
• increased B cell derived lymphoma incidence_H2afx<tm1Fwa>/H2afx<tm1Fwa>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002023I129S6SvEvTac129S7SvEvBrdC57BL6H2afxtm1FwaH2afxtm1FwaTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdH2afxtm1Fwa
• increased T cell derived lymphoma incidence_H2afx<tm1Fwa>/H2afx<tm1Fwa>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002024I129S6SvEvTac129S7SvEvBrdC57BL6H2afxtm1FwaH2afxtm1FwaTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdH2afxtm1Fwa
• increased lymphoma incidence_H2afx<tm1Fwa>/H2afx<+>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0012431I129S6SvEvTac129S7SvEvBrdC57BL6H2afxtm1FwaH2afxTrp53tm1BrdTrp53tm1BrdH2afxTrp53tm1BrdH2afxtm1Fwa
• increased sarcoma incidence_H2afx<tm1Fwa>/H2afx<+>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002032I129S6SvEvTac129S7SvEvBrdC57BL6H2afxtm1FwaH2afxTrp53tm1BrdTrp53tm1BrdH2afxTrp53tm1BrdH2afxtm1Fwa
• increased T cell derived lymphoma incidence_H2afx<tm1Fwa>/H2afx<+>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002024I129S6SvEvTac129S7SvEvBrdC57BL6H2afxtm1FwaH2afxTrp53tm1BrdTrp53tm1BrdH2afxTrp53tm1BrdH2afxtm1Fwa
• abnormal class switch recombination_H2afx<tm1Fwa>/H2afx<tm1Fwa>
  http://metadb.riken.jp/0004816I129S6SvEvTacH2afxtm1FwaH2afxtm1FwaH2afxtm1Fwa
• premature death_H2afx<tm1Fwa>/H2afx<tm1Fwa>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002083I129S6SvEvTac129S7SvEvBrdC57BL6H2afxtm1FwaH2afxtm1FwaTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdH2afxtm1Fwa
• increased colon adenocarcinoma incidence_H2afx<tm1Fwa>/H2afx<tm1Fwa>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0009314I129S6SvEvTac129S7SvEvBrdC57BL6H2afxtm1FwaH2afxtm1FwaTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdH2afxtm1Fwa
• chromosomal instability_H2afx<tm1Fwa>/H2afx<+>
  http://metadb.riken.jp/0008866I129S6SvEvTacH2afxtm1FwaH2afxH2afxH2afxtm1Fwa
• chromosomal instability_H2afx<tm1Fwa>/H2afx<tm1Fwa>
  http://metadb.riken.jp/0008866I129S6SvEvTacH2afxtm1FwaH2afxtm1FwaH2afxtm1Fwa
• decreased lymphocyte cell number_H2afx<tm1Fwa>/H2afx<tm1Fwa>
  http://metadb.riken.jp/0005016I129S6SvEvTacH2afxtm1FwaH2afxtm1FwaH2afxtm1Fwa
• increased tumor incidence_H2afx<tm1Fwa>/H2afx<tm1Fwa>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002020I129S6SvEvTac129S7SvEvBrdC57BL6H2afxtm1FwaH2afxtm1FwaTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdH2afxtm1Fwa
• increased sarcoma incidence_H2afx<tm1Fwa>/H2afx<tm1Fwa>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0002032I129S6SvEvTac129S7SvEvBrdC57BL6H2afxtm1FwaH2afxtm1FwaTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdH2afxtm1Fwa
• decreased body size_H2afx<tm1Fwa>/H2afx<tm1Fwa>
  http://metadb.riken.jp/0001265I129S6SvEvTacH2afxtm1FwaH2afxtm1FwaH2afxtm1Fwa

class

http://purl.org/net/cito/citesAsAuthority

• H2afx<tm1Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2670743