Kazuyuki. Yoshida, et.al., Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality., The Journal of biological chemistry, 2004, 279

http://rdf.ncbi.nlm.nih.gov/pubmed/14645240

Kazuyuki. Yoshida, et.al., Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality., The Journal of biological chemistry, 2004, 279

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3769591

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• absent olfactory bulb_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0003451I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu
• abnormal embryonic/fetal subventricular zone morphology_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0004274I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu
• decreased embryo size_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0001698I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu
• abnormal nervous system development_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0003861I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu
• absent cerebellum_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0000850I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu
• abnormal embryonic neuroepithelial layer differentiation_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0000786I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu
• abnormal neuron differentiation_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0009937I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu
• abnormal brain development_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0000913I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu
• embryonic lethality during organogenesis, complete penetrance_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0011098I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu
• decreased brain size_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0000774I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu
• forebrain hypoplasia_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0000784I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu
• enlarged lateral ventricles_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0008535I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu
• interdigital webbing_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0000571I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu
• exencephaly_Phgdh<tm1.1Shfu>/Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/0000914I129P2OlaHsdC57BL6JFVBNPhgdhtm11ShfuPhgdhtm11ShfuPhgdhtm11Shfu

class

http://purl.org/net/cito/citesAsAuthority

• Phgdh<tm1.1Shfu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3769591

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD03097
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03097
• CD03098
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03098

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]
• [Blank]

BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• B6;129P2-Phgdh<tm1Bsi>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC02150
• B6;129P2-Phgdh<tm2Bsi>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC02574

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal neuron differentiation in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003784
• forebrain hypoplasia in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003774
• abnormal nervous system development in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003781
• enlarged lateral ventricles in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003783
• exencephaly in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003778
• decreased brain size in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003773
• absent olfactory bulb in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003780
• abnormal embryonic neuroepithelial layer differentiation in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003775
• abnormal embryonic/fetal subventricular zone morphology in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003782
• decreased embryo size in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003779
• abnormal brain development in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003777
• absent cerebellum in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003776
• interdigital webbing in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003772
• embryonic lethality during organogenesis, complete penetrance in RBRC02150
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003785

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]
• [Blank]