Andrew J. Aguirre, et.al., Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma., Genes & development, 2003, 17

http://rdf.ncbi.nlm.nih.gov/pubmed/14681207

Andrew J. Aguirre, et.al., Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma., Genes & development, 2003, 17

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cdkn2a<tm4Rdp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2687203

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009152I129S4SvJaeC57BL6CBAKrastm4TyjKrasTgPdx1cre891Dam0TgPdx1cre891DamKrastm4TyjKras
• increased metastatic potential_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0001272I129S4SvJaeC57BL6CBAFVBNCdkn2atm4RdpCdkn2atm4RdpKrastm4TyjKrasTgPdx1cre891Dam0Cdkn2atm4RdpKrastm4TyjTgPdx1cre891DamKras
• premature death_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6CBAFVBNCdkn2atm4RdpCdkn2atm4RdpKrastm4TyjKrasTgPdx1cre891Dam0Cdkn2atm4RdpKrastm4TyjTgPdx1cre891DamKras
• increased malignant tumor incidence_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0002018I129S4SvJaeC57BL6CBAFVBNCdkn2atm4RdpCdkn2atm4RdpKrastm4TyjKrasTgPdx1cre891Dam0Cdkn2atm4RdpKrastm4TyjTgPdx1cre891DamKras
• increased pancreatic intraepithelial neoplasia incidence_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009152I129S4SvJaeC57BL6CBAFVBNCdkn2atm4RdpCdkn2atm4RdpKrastm4TyjKrasTgPdx1cre891Dam0Cdkn2atm4RdpKrastm4TyjTgPdx1cre891DamKras
• increased pancreatic ductal adenocarcinoma incidence_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009151I129S4SvJaeC57BL6CBAFVBNCdkn2atm4RdpCdkn2atm4RdpKrastm4TyjKrasTgPdx1cre891Dam0Cdkn2atm4RdpKrastm4TyjTgPdx1cre891DamKras
• enlarged pancreatic islets_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009171I129S4SvJaeC57BL6CBAKrastm4TyjKrasTgPdx1cre891Dam0TgPdx1cre891DamKrastm4TyjKras
• increased pancreas tumor incidence_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009153I129S4SvJaeC57BL6CBAFVBNCdkn2atm4RdpCdkn2atm4RdpKrastm4TyjKrasTgPdx1cre891Dam0Cdkn2atm4RdpKrastm4TyjTgPdx1cre891DamKras

class

http://purl.org/net/cito/citesAsAuthority

• Cdkn2a<tm4Rdp>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2687203