Joel R. Neilson, et.al., Calcineurin B1 is essential for positive but not negative selection during thymocyte development., Immunity, 2004, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/15030770

Joel R. Neilson, et.al., Calcineurin B1 is essential for positive but not negative selection during thymocyte development., Immunity, 2004, 20

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ppp3r1<tm2Grc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044022
• Ppp3r1<tm2.1Grc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044031

class

http://purl.org/net/cito/citesAsAuthority

• Ppp3r1<tm2Grc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044022
• Ppp3r1<tm2.1Grc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3044031

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• thymus hypoplasia_Ppp3r1<tm2Grc>/Ppp3r1<tm2Grc>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0001823I129S6SvEvTacC57BL6DBA2Ppp3r1tm2GrcPpp3r1tm2GrcTgLckcre1Cwi0TgLckcre1CwiPpp3r1tm2Grc
• abnormal visceral yolk sac morphology_Ppp3r1<tm2.1Grc>/Ppp3r1<tm2.1Grc>
  http://metadb.riken.jp/0001718NSPpp3r1tm21GrcPpp3r1tm21GrcPpp3r1tm21Grc
• abnormal enzyme/coenzyme activity_Ppp3r1<tm2Grc>/Ppp3r1<tm2.1Grc>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0005584I129S6SvEvTacC57BL6DBA2Ppp3r1tm2GrcPpp3r1tm21GrcTgLckcre1Cwi0Ppp3r1tm2GrcTgLckcre1CwiPpp3r1tm21Grc
• absent vitelline blood vessels_Ppp3r1<tm2.1Grc>/Ppp3r1<tm2.1Grc>
  http://metadb.riken.jp/0001719NSPpp3r1tm21GrcPpp3r1tm21GrcPpp3r1tm21Grc
• abnormal angiogenesis_Ppp3r1<tm2.1Grc>/Ppp3r1<tm2.1Grc>
  http://metadb.riken.jp/0000260NSPpp3r1tm21GrcPpp3r1tm21GrcPpp3r1tm21Grc
• abnormal heart morphology_Ppp3r1<tm2.1Grc>/Ppp3r1<tm2.1Grc>
  http://metadb.riken.jp/0000266NSPpp3r1tm21GrcPpp3r1tm21GrcPpp3r1tm21Grc
• abnormal positive T cell selection_Ppp3r1<tm2Grc>/Ppp3r1<tm2.1Grc>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0004919I129S6SvEvTacC57BL6DBA2Ppp3r1tm2GrcPpp3r1tm21GrcTgLckcre1Cwi0Ppp3r1tm2GrcTgLckcre1CwiPpp3r1tm21Grc
• distended pericardium_Ppp3r1<tm2.1Grc>/Ppp3r1<tm2.1Grc>
  http://metadb.riken.jp/0000292NSPpp3r1tm21GrcPpp3r1tm21GrcPpp3r1tm21Grc
• abnormal blood vessel morphology_Ppp3r1<tm2.1Grc>/Ppp3r1<tm2.1Grc>
  http://metadb.riken.jp/0001614NSPpp3r1tm21GrcPpp3r1tm21GrcPpp3r1tm21Grc
• decreased embryo size_Ppp3r1<tm2.1Grc>/Ppp3r1<tm2.1Grc>
  http://metadb.riken.jp/0001698NSPpp3r1tm21GrcPpp3r1tm21GrcPpp3r1tm21Grc
• abnormal extraembryonic tissue morphology_Ppp3r1<tm2.1Grc>/Ppp3r1<tm2.1Grc>
  http://metadb.riken.jp/0002086NSPpp3r1tm21GrcPpp3r1tm21GrcPpp3r1tm21Grc
• disorganized yolk sac vascular plexus_Ppp3r1<tm2.1Grc>/Ppp3r1<tm2.1Grc>
  http://metadb.riken.jp/0001723NSPpp3r1tm21GrcPpp3r1tm21GrcPpp3r1tm21Grc
• abnormal splenic cell ratio_Ppp3r1<tm2Grc>/Ppp3r1<tm2.1Grc>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008826I129S6SvEvTacC57BL6DBA2Ppp3r1tm2GrcPpp3r1tm21GrcTgLckcre1Cwi0Ppp3r1tm2GrcTgLckcre1CwiPpp3r1tm21Grc
• decreased thymocyte number_Ppp3r1<tm2Grc>/Ppp3r1<tm2Grc>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0000715I129S6SvEvTacC57BL6DBA2Ppp3r1tm2GrcPpp3r1tm2GrcTgLckcre1Cwi0TgLckcre1CwiPpp3r1tm2Grc
• abnormal lymph node cell ratio_Ppp3r1<tm2Grc>/Ppp3r1<tm2.1Grc>,Tg(Lck-cre)1Cwi/0
  http://metadb.riken.jp/0008828I129S6SvEvTacC57BL6DBA2Ppp3r1tm2GrcPpp3r1tm21GrcTgLckcre1Cwi0Ppp3r1tm2GrcTgLckcre1CwiPpp3r1tm21Grc
• embryonic lethality during organogenesis, complete penetrance_Ppp3r1<tm2.1Grc>/Ppp3r1<tm2.1Grc>
  http://metadb.riken.jp/0011098NSPpp3r1tm21GrcPpp3r1tm21GrcPpp3r1tm21Grc