Y. Shinkai, et.al., RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement., Cell, 1992, 68

http://rdf.ncbi.nlm.nih.gov/pubmed/1547487

Y. Shinkai, et.al., RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement., Cell, 1992, 68

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rag2<tm1Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1858556

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal T cell receptor V(D)J recombination_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0008754I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• thymus hypoplasia_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0001823I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• increased susceptibility to infection_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0002406I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• lymph node hypoplasia_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0008101I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• decreased CD8-positive, alpha-beta T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0008079I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• abnormal effector T cell morphology_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0002435I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• decreased double-positive T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0005092I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• abnormal spleen morphology_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0000689I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• decreased CD4-positive, alpha beta T cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0008075I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• arrested B cell differentiation_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0001802I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• absent mature B cells_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0008212I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• decreased IgM level_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0001806I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• spleen hypoplasia_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0000694I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• increased natural killer cell mediated cytotoxicity_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0003080I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• increased granulocyte number_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0000322I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• increased macrophage cell number_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0005425I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• arrested T cell differentiation_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0001825I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• abnormal immunoglobulin V(D)J recombination_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0008755I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa
• decreased body size_Rag2<tm1Fwa>/Rag2<tm1Fwa>
  http://metadb.riken.jp/0001265I129SSvEvMF1Rag2tm1FwaRag2tm1FwaRag2tm1Fwa

class

http://purl.org/net/cito/citesAsAuthority

• Rag2<tm1Fwa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1858556

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD16282
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16282

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]

BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• B6;129-Rag2<tm1Fwa> Il2rb<tm1Mak>/Rbrc
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC00522

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• spleen hypoplasia in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1012967
• increased natural killer cell mediated cytotoxicity in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1012997
• increased susceptibility to infection in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1012987
• abnormal effector T cell morphology in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1012989
• abnormal thymus morphology in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014842
• increased macrophage cell number in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1013011
• abnormal immunoglobulin V(D)J recombination in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1013040
• absent mature B cells in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1013030
• abnormal T cell receptor V(D)J recombination in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1013039
• arrested B cell differentiation in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1012974
• small lymph nodes in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014840
• decreased IgM level in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1012975
• abnormal lymph node morphology in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014843
• small spleen in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014841
• decreased CD4-positive, alpha beta T cell number in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1013021
• abnormal spleen morphology in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1012965
• lymph node hypoplasia in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1013026
• decreased body size in RBRC00522
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1012971

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]