Nguyet M. Nguyen, et.al., Epithelial laminin alpha5 is necessary for distal epithelial cell maturation, VEGF production, and alveolization in the developing murine lung., Developmental biology, 2005, 282

http://rdf.ncbi.nlm.nih.gov/pubmed/15936333

Nguyet M. Nguyen, et.al., Epithelial laminin alpha5 is necessary for distal epithelial cell maturation, VEGF production, and alveolization in the developing murine lung., Developmental biology, 2005, 282

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lama5<tm2Jhm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3613037
• Lama5<tm3Jhm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3823246

class

http://purl.org/net/cito/citesAsAuthority

• Lama5<tm2Jhm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3613037
• Lama5<tm3Jhm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3823246

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal lung vasculature morphology_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0004007I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• respiratory distress_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0001954I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• thin lung-associated mesenchyme_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0011144I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• pulmonary hypoplasia_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0001178I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• abnormal pulmonary alveolus epithelium morphology_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0010898I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• neonatal lethality, complete penetrance_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0011087I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• respiratory failure_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0001953I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• abnormal lung development_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0001176I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• absent type I pneumocytes_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0010817I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• decreased cell proliferation_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0000352I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• overexpanded pulmonary alveoli_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0001183I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• decreased type II pneumocyte number_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0010811I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• abnormal pulmonary alveolus morphology_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0002270I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• increased apoptosis_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0006042I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw
• cyanosis_Lama5<tm1Jhm>/Lama5<tm2Jhm>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?
  http://metadb.riken.jp/0001575I129S1Sv129X1SvJLama5tm1JhmLama5tm2JhmTgSFTPCrtTA5JawTgtetOcre1JawLama5tm2JhmLama5tm1JhmTgSFTPCrtTA5JawTgtetOcre1Jaw