Zhenbang. Chen, et.al., Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis., Nature, 2005, 436

http://rdf.ncbi.nlm.nih.gov/pubmed/16079851

Zhenbang. Chen, et.al., Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis., Nature, 2005, 436

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Trp53<tm1Thl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3589921

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• urinary bladder obstruction_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Trp53<tm1Thl>/Trp53<tm1Thl>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0009552I129S1SvC57BL6DBA2Ptentm21PppPtentm21PppTrp53tm1ThlTrp53tm1ThlTgPbsncre4Prb0Ptentm21PppTgPbsncre4PrbTrp53tm1Thl
• increased prostate gland adenocarcinoma incidence_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0009220I129S1SvC57BL6DBA2Ptentm21PppPtentm21PppTgPbsncre4Prb0Ptentm21PppTgPbsncre4Prb
• increased carcinoma incidence_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Trp53<tm1Thl>/Trp53<tm1Thl>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0002038I129S1SvC57BL6DBA2Ptentm21PppPtentm21PppTrp53tm1ThlTrp53tm1ThlTgPbsncre4Prb0Ptentm21PppTgPbsncre4PrbTrp53tm1Thl
• kidney failure_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Trp53<tm1Thl>/Trp53<tm1Thl>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0003606I129S1SvC57BL6DBA2Ptentm21PppPtentm21PppTrp53tm1ThlTrp53tm1ThlTgPbsncre4Prb0Ptentm21PppTgPbsncre4PrbTrp53tm1Thl
• prostate gland epithelial hyperplasia_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0001167I129S1SvC57BL6DBA2Ptentm21PppPtentm21PppTgPbsncre4Prb0Ptentm21PppTgPbsncre4Prb
• increased prostate gland tumor incidence_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0010357I129S1SvC57BL6DBA2Ptentm21PppPtentm21PppTgPbsncre4Prb0Ptentm21PppTgPbsncre4Prb
• premature death_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Trp53<tm1Thl>/Trp53<tm1Thl>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0002083I129S1SvC57BL6DBA2Ptentm21PppPtentm21PppTrp53tm1ThlTrp53tm1ThlTgPbsncre4Prb0Ptentm21PppTgPbsncre4PrbTrp53tm1Thl
• increased prostate gland tumor incidence_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Trp53<tm1Thl>/Trp53<tm1Thl>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0010357I129S1SvC57BL6DBA2Ptentm21PppPtentm21PppTrp53tm1ThlTrp53tm1ThlTgPbsncre4Prb0Ptentm21PppTgPbsncre4PrbTrp53tm1Thl
• increased prostate intraepithelial neoplasia incidence_Pten<tm2.1Ppp>/Pten<tm2.1Ppp>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0009219I129S1SvC57BL6DBA2Ptentm21PppPtentm21PppTgPbsncre4Prb0Ptentm21PppTgPbsncre4Prb

class

http://purl.org/net/cito/citesAsAuthority

• Trp53<tm1Thl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3589921