Ya-Huei. Kuo, et.al., Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia., Cancer cell, 2006, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/16413472

Ya-Huei. Kuo, et.al., Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia., Cancer cell, 2006, 9

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal liver morphology_Cbfb<tm1Lhc>/Cbfb<tm1Lhc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000598I129S6SvEvTacC57BL6CBACbfbtm1LhcCbfbtm1LhcTgMx1cre1Cgn0Cbfbtm1LhcTgMx1cre1Cgn
• anemia_Cbfb<tm1Lhc>/Cbfb<tm1Lhc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001577I129S6SvEvTacC57BL6CBACbfbtm1LhcCbfbtm1LhcTgMx1cre1Cgn0Cbfbtm1LhcTgMx1cre1Cgn
• increased leukocyte cell number_Cbfb<tm1Lhc>/Cbfb<tm1Lhc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000218I129S6SvEvTacC57BL6CBACbfbtm1LhcCbfbtm1LhcTgMx1cre1Cgn0Cbfbtm1LhcTgMx1cre1Cgn
• enlarged spleen_Cbfb<tm1Lhc>/Cbfb<tm1Lhc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000691I129S6SvEvTacC57BL6CBACbfbtm1LhcCbfbtm1LhcTgMx1cre1Cgn0Cbfbtm1LhcTgMx1cre1Cgn
• abnormal myelopoiesis_Cbfb<tm1Lhc>/Cbfb<tm1Lhc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0001601I129S6SvEvTacC57BL6CBACbfbtm1LhcCbfbtm1LhcTgMx1cre1Cgn0Cbfbtm1LhcTgMx1cre1Cgn
• abnormal megakaryocyte differentiation_Cbfb<tm1Lhc>/Cbfb<tm1Lhc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000229I129S6SvEvTacC57BL6CBACbfbtm1LhcCbfbtm1LhcTgMx1cre1Cgn0Cbfbtm1LhcTgMx1cre1Cgn
• impaired hematopoiesis_Cbfb<tm1Lhc>/Cbfb<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0001606I129S6SvEvTacC57BL6FVBNCbfbtm1LhcCbfbTgEIIacreC5379Lmgd0TgEIIacreC5379LmgdCbfbCbfbtm1Lhc
• thrombocytopenia_Cbfb<tm1Lhc>/Cbfb<tm1Lhc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0003179I129S6SvEvTacC57BL6CBACbfbtm1LhcCbfbtm1LhcTgMx1cre1Cgn0Cbfbtm1LhcTgMx1cre1Cgn
• embryonic lethality, complete penetrance_Cbfb<tm1Lhc>/Cbfb<+>,Tg(EIIa-cre)C5379Lmgd/0
  http://metadb.riken.jp/0011092I129S6SvEvTacC57BL6FVBNCbfbtm1LhcCbfbTgEIIacreC5379Lmgd0TgEIIacreC5379LmgdCbfbCbfbtm1Lhc
• abnormal spleen morphology_Cbfb<tm1Lhc>/Cbfb<tm1Lhc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000689I129S6SvEvTacC57BL6CBACbfbtm1LhcCbfbtm1LhcTgMx1cre1Cgn0Cbfbtm1LhcTgMx1cre1Cgn
• increased hematopoietic stem cell number_Cbfb<tm1Lhc>/Cbfb<tm1Lhc>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0004809I129S6SvEvTacC57BL6CBACbfbtm1LhcCbfbtm1LhcTgMx1cre1Cgn0Cbfbtm1LhcTgMx1cre1Cgn