Kyoichi. Isono, et.al., Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals., Molecular and cellular biology, 2006, 26

http://rdf.ncbi.nlm.nih.gov/pubmed/16537918

Kyoichi. Isono, et.al., Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals., Molecular and cellular biology, 2006, 26

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hipk2<tm1Hko>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3624127
• Hipk1<tm1Hko>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3624126

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal neural tube morphology_Hipk1<tm1Hko>/Hipk1<tm1Hko>
  http://metadb.riken.jp/0002151IC57BL6Hipk1tm1HkoHipk1tm1HkoHipk1tm1Hko
• decreased cellular sensitivity to ultraviolet irradiation_Hipk2<tm1Hko>/Hipk2<tm1Hko>
  http://metadb.riken.jp/0008411IC57BL6Hipk2tm1HkoHipk2tm1HkoHipk2tm1Hko
• exencephaly_Hipk1<tm1Hko>/Hipk1<tm1Hko>,Hipk2<tm1Hko>/Hipk2<tm1Hko>,Trp53<tm2Mok>/Trp53<+>
  http://metadb.riken.jp/0000914I129SSvEvC57BL6Hipk1tm1HkoHipk1tm1HkoHipk2tm1HkoHipk2tm1HkoTrp53tm2MokTrp53Trp53Hipk1tm1HkoHipk2tm1HkoTrp53tm2Mok
• abnormal neural tube morphology_Hipk1<tm1Hko>/Hipk1<tm1Hko>,Hipk2<tm1Hko>/Hipk2<tm1Hko>
  http://metadb.riken.jp/0002151IC57BL6Hipk1tm1HkoHipk1tm1HkoHipk2tm1HkoHipk2tm1HkoHipk2tm1HkoHipk1tm1Hko
• abnormal neural tube morphology_Hipk1<tm1Hko>/Hipk1<tm1Hko>,Hipk2<tm1Hko>/Hipk2<+>
  http://metadb.riken.jp/0002151IC57BL6Hipk1tm1HkoHipk1tm1HkoHipk2tm1HkoHipk2Hipk2Hipk1tm1HkoHipk2tm1Hko
• embryonic growth retardation_Hipk1<tm1Hko>/Hipk1<tm1Hko>,Hipk2<tm1Hko>/Hipk2<tm1Hko>
  http://metadb.riken.jp/0003984IC57BL6Hipk1tm1HkoHipk1tm1HkoHipk2tm1HkoHipk2tm1HkoHipk2tm1HkoHipk1tm1Hko
• abnormal lens vesicle development_Hipk1<tm1Hko>/Hipk1<tm1Hko>,Hipk2<tm1Hko>/Hipk2<tm1Hko>
  http://metadb.riken.jp/0001292IC57BL6Hipk1tm1HkoHipk1tm1HkoHipk2tm1HkoHipk2tm1HkoHipk2tm1HkoHipk1tm1Hko
• exencephaly_Hipk1<tm1Hko>/Hipk1<tm1Hko>,Hipk2<tm1Hko>/Hipk2<+>
  http://metadb.riken.jp/0000914IC57BL6Hipk1tm1HkoHipk1tm1HkoHipk2tm1HkoHipk2Hipk2Hipk1tm1HkoHipk2tm1Hko
• embryonic lethality during organogenesis, incomplete penetrance_Hipk1<tm1Hko>/Hipk1<+>,Hipk2<tm1Hko>/Hipk2<tm1Hko>
  http://metadb.riken.jp/0011108IC57BL6Hipk1tm1HkoHipk1Hipk2tm1HkoHipk2tm1HkoHipk1Hipk2tm1HkoHipk1tm1Hko
• embryonic lethality during organogenesis_Hipk1<tm1Hko>/Hipk1<tm1Hko>,Hipk2<tm1Hko>/Hipk2<tm1Hko>
  http://metadb.riken.jp/0006207IC57BL6Hipk1tm1HkoHipk1tm1HkoHipk2tm1HkoHipk2tm1HkoHipk2tm1HkoHipk1tm1Hko
• increased apoptosis_Hipk1<tm1Hko>/Hipk1<tm1Hko>,Hipk2<tm1Hko>/Hipk2<tm1Hko>
  http://metadb.riken.jp/0006042IC57BL6Hipk1tm1HkoHipk1tm1HkoHipk2tm1HkoHipk2tm1HkoHipk2tm1HkoHipk1tm1Hko
• exencephaly_Hipk1<tm1Hko>/Hipk1<tm1Hko>,Hipk2<tm1Hko>/Hipk2<tm1Hko>
  http://metadb.riken.jp/0000914IC57BL6Hipk1tm1HkoHipk1tm1HkoHipk2tm1HkoHipk2tm1HkoHipk2tm1HkoHipk1tm1Hko
• decreased cell proliferation_Hipk1<tm1Hko>/Hipk1<tm1Hko>,Hipk2<tm1Hko>/Hipk2<tm1Hko>
  http://metadb.riken.jp/0000352IC57BL6Hipk1tm1HkoHipk1tm1HkoHipk2tm1HkoHipk2tm1HkoHipk2tm1HkoHipk1tm1Hko
• abnormal neural tube morphology_Hipk2<tm1Hko>/Hipk2<tm1Hko>
  http://metadb.riken.jp/0002151IC57BL6Hipk2tm1HkoHipk2tm1HkoHipk2tm1Hko
• abnormal neural tube morphology_Hipk1<tm1Hko>/Hipk1<+>,Hipk2<tm1Hko>/Hipk2<tm1Hko>
  http://metadb.riken.jp/0002151IC57BL6Hipk1tm1HkoHipk1Hipk2tm1HkoHipk2tm1HkoHipk1Hipk2tm1HkoHipk1tm1Hko
• decreased cellular sensitivity to ultraviolet irradiation_Trp53<tm2Mok>/Trp53<+>
  http://metadb.riken.jp/0008411I129SSvEvC57BL6Trp53tm2MokTrp53Trp53Trp53tm2Mok
• decreased cellular sensitivity to ultraviolet irradiation_Hipk1<tm1Hko>/Hipk1<+>,Hipk2<tm1Hko>/Hipk2<tm1Hko>
  http://metadb.riken.jp/0008411IC57BL6Hipk1tm1HkoHipk1Hipk2tm1HkoHipk2tm1HkoHipk1Hipk2tm1HkoHipk1tm1Hko
• decreased cellular sensitivity to ultraviolet irradiation_Hipk1<tm1Hko>/Hipk1<tm1Hko>
  http://metadb.riken.jp/0008411IC57BL6Hipk1tm1HkoHipk1tm1HkoHipk1tm1Hko

class

http://purl.org/net/cito/citesAsAuthority

• Hipk2<tm1Hko>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3624127
• Hipk1<tm1Hko>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3624126

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD01085
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01085

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased cellular sensitivity to ultraviolet irradiation in RBRC02260
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1003954
• decreased cellular sensitivity to ultraviolet irradiation in RBRC02428
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1013551