Yusuke. Watanabe, et.al., Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse., Development (Cambridge, England), 2006, 133

http://rdf.ncbi.nlm.nih.gov/pubmed/16554359

Yusuke. Watanabe, et.al., Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse., Development (Cambridge, England), 2006, 133

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(CAG-cat,-Notch1)1Ysa
  http://metadb.riken.jp/db/mgi_rdf/MGI:3702441

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal myocardium layer morphology_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0005329IC3HC57BL6CBAMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1Mesp1tm2creYsaTgCAGcatNotch11Ysa
• abnormal trabecula carnea morphology_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0004067IC3HC57BL6CBAMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1Mesp1tm2creYsaTgCAGcatNotch11Ysa
• abnormal myocardial fiber morphology_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0000278IC3HC57BL6CBAMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1Mesp1tm2creYsaTgCAGcatNotch11Ysa
• abnormal interventricular septum morphology_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0000281IC3HC57BL6CBAMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1Mesp1tm2creYsaTgCAGcatNotch11Ysa
• abnormal heart development_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0000267IC3HC57BL6CBAMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1Mesp1tm2creYsaTgCAGcatNotch11Ysa
• abnormal atrioventricular cushion morphology_Hey1<tm1Kkb>/Hey1<tm1Kkb>,Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0000297I129S7SvEvBrdC3HC57BL6CBAHey1tm1KkbHey1tm1KkbMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1tm2creYsaTgCAGcatNotch11YsaHey1tm1KkbMesp1
• embryonic lethality during organogenesis, complete penetrance_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0011098IC3HC57BL6CBAMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1Mesp1tm2creYsaTgCAGcatNotch11Ysa
• abnormal heart ventricle morphology_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0005294IC3HC57BL6CBAMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1Mesp1tm2creYsaTgCAGcatNotch11Ysa
• dilated heart left ventricle_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0002753IC3HC57BL6CBAMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1Mesp1tm2creYsaTgCAGcatNotch11Ysa
• decreased heart right ventricle size_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0003649IC3HC57BL6CBAMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1Mesp1tm2creYsaTgCAGcatNotch11Ysa
• abnormal atrioventricular cushion morphology_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0000297IC3HC57BL6CBAMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1Mesp1tm2creYsaTgCAGcatNotch11Ysa
• abnormal sarcomere morphology_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0004090IC3HC57BL6CBAMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1Mesp1tm2creYsaTgCAGcatNotch11Ysa
• abnormal heart shape_Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0000277IC3HC57BL6CBAMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1Mesp1tm2creYsaTgCAGcatNotch11Ysa
• abnormal interventricular septum morphology_Hey1<tm1Kkb>/Hey1<tm1Kkb>,Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0000281I129S7SvEvBrdC3HC57BL6CBAHey1tm1KkbHey1tm1KkbMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1tm2creYsaTgCAGcatNotch11YsaHey1tm1KkbMesp1
• abnormal myocardial trabeculae morphology_Hey1<tm1Kkb>/Hey1<tm1Kkb>,Mesp1<tm2(cre)Ysa>/Mesp1<+>,Tg(CAG-cat,-Notch1)1Ysa/0
  http://metadb.riken.jp/0002189I129S7SvEvBrdC3HC57BL6CBAHey1tm1KkbHey1tm1KkbMesp1tm2creYsaMesp1TgCAGcatNotch11Ysa0Mesp1tm2creYsaTgCAGcatNotch11YsaHey1tm1KkbMesp1

class

http://purl.org/net/cito/citesAsAuthority

• Tg(CAG-cat,-Notch1)1Ysa
  http://metadb.riken.jp/db/mgi_rdf/MGI:3702441