Nabeel. Bardeesy, et.al., Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103

http://rdf.ncbi.nlm.nih.gov/pubmed/16585505

Nabeel. Bardeesy, et.al., Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased pancreas tumor incidence_Cdkn2a<tm4Rdp>/Cdkn2a<+>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009153I129S4SvJaeC57BL6CBAFVBNCdkn2atm4RdpCdkn2aKrastm4TyjKrasTgPdx1cre891Dam0Cdkn2aCdkn2atm4RdpKrasKrastm4TyjTgPdx1cre891Dam
• increased metastatic potential_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0001272I129C57BL6CBAFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTgPdx1cre891Dam0TgPdx1cre891DamKrastm4TyjKrasCdkn2atm21Rdp
• increased pancreas tumor incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009153I129C57BL6CBAFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTrp53tm1BrnTrp53TgPdx1cre891Dam0KrasCdkn2atm21RdpTgPdx1cre891DamKrastm4TyjTrp53tm1BrnTrp53
• increased pancreatic ductal adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009151I129C57BL6CBAFVBNKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnTgPdx1cre891Dam0Trp53tm1BrnKrasTgPdx1cre891DamKrastm4Tyj
• increased pancreas tumor incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009153I129C57BL6CBAFVBNKrastm4TyjKrasTrp53tm1BrnTrp53TgPdx1cre891Dam0KrasKrastm4TyjTgPdx1cre891DamTrp53tm1BrnTrp53
• increased pancreatic ductal adenocarcinoma incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009151I129C57BL6CBAFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnTgPdx1cre891Dam0Trp53tm1BrnKrasCdkn2atm21RdpTgPdx1cre891DamKrastm4Tyj
• increased pancreatic ductal adenocarcinoma incidence_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009151I129S4SvJaeC57BL6CBAFVBNCdkn2atm4RdpCdkn2atm4RdpKrastm4TyjKrasTgPdx1cre891Dam0Cdkn2atm4RdpKrastm4TyjTgPdx1cre891DamKras
• increased pancreatic ductal adenocarcinoma incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<+>,Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009151I129C57BL6CBAFVBNCdkn2atm21RdpCdkn2aKrastm4TyjKrasTrp53tm1BrnTrp53TgPdx1cre891Dam0Trp53Cdkn2aKrasCdkn2atm21RdpTgPdx1cre891DamKrastm4TyjTrp53tm1Brn
• increased metastatic potential_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0001272I129C57BL6CBAFVBNKrastm4TyjKrasTrp53tm1BrnTrp53TgPdx1cre891Dam0KrasKrastm4TyjTgPdx1cre891DamTrp53tm1BrnTrp53
• increased pancreatic ductal adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009151I129C57BL6CBAFVBNKrastm4TyjKrasTrp53tm1BrnTrp53TgPdx1cre891Dam0KrasKrastm4TyjTgPdx1cre891DamTrp53tm1BrnTrp53
• increased metastatic potential_Cdkn2a<tm4Rdp>/Cdkn2a<+>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0001272I129S4SvJaeC57BL6CBAFVBNCdkn2atm4RdpCdkn2aKrastm4TyjKrasTgPdx1cre891Dam0Cdkn2aCdkn2atm4RdpKrasKrastm4TyjTgPdx1cre891Dam
• increased metastatic potential_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0001272I129S4SvJaeC57BL6CBAFVBNCdkn2atm4RdpCdkn2atm4RdpKrastm4TyjKrasTgPdx1cre891Dam0Cdkn2atm4RdpKrastm4TyjTgPdx1cre891DamKras
• increased pancreas tumor incidence_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009153I129S4SvJaeC57BL6CBAFVBNKrastm4TyjKrasTgPdx1cre891Dam0Krastm4TyjTgPdx1cre891DamKras
• increased metastatic potential_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0001272I129C57BL6CBAFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTrp53tm1BrnTrp53TgPdx1cre891Dam0KrasCdkn2atm21RdpTgPdx1cre891DamKrastm4TyjTrp53tm1BrnTrp53
• increased pancreas tumor incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009153I129C57BL6CBAFVBNKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnTgPdx1cre891Dam0Trp53tm1BrnKrasTgPdx1cre891DamKrastm4Tyj
• increased pancreatic ductal adenocarcinoma incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009151I129C57BL6CBAFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTrp53tm1BrnTrp53TgPdx1cre891Dam0KrasCdkn2atm21RdpTgPdx1cre891DamKrastm4TyjTrp53tm1BrnTrp53
• increased pancreas tumor incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<+>,Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009153I129C57BL6CBAFVBNCdkn2atm21RdpCdkn2aKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnTgPdx1cre891Dam0Cdkn2aTrp53tm1BrnKrasCdkn2atm21RdpTgPdx1cre891DamKrastm4Tyj
• increased metastatic potential_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0001272I129C57BL6CBAFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnTgPdx1cre891Dam0Trp53tm1BrnKrasCdkn2atm21RdpTgPdx1cre891DamKrastm4Tyj
• increased pancreas tumor incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<+>,Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009153I129C57BL6CBAFVBNCdkn2atm21RdpCdkn2aKrastm4TyjKrasTrp53tm1BrnTrp53TgPdx1cre891Dam0Trp53Cdkn2aKrasCdkn2atm21RdpTgPdx1cre891DamKrastm4TyjTrp53tm1Brn
• increased pancreas tumor incidence_Cdkn2a<tm4Rdp>/Cdkn2a<tm4Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009153I129S4SvJaeC57BL6CBAFVBNCdkn2atm4RdpCdkn2atm4RdpKrastm4TyjKrasTgPdx1cre891Dam0Cdkn2atm4RdpKrastm4TyjTgPdx1cre891DamKras
• increased pancreas tumor incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009153I129C57BL6CBAFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTgPdx1cre891Dam0TgPdx1cre891DamKrastm4TyjKrasCdkn2atm21Rdp
• increased pancreas tumor incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009153I129C57BL6CBAFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnTgPdx1cre891Dam0Trp53tm1BrnKrasCdkn2atm21RdpTgPdx1cre891DamKrastm4Tyj
• increased pancreatic ductal adenocarcinoma incidence_Cdkn2a<tm4Rdp>/Cdkn2a<+>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009151I129S4SvJaeC57BL6CBAFVBNCdkn2atm4RdpCdkn2aKrastm4TyjKrasTgPdx1cre891Dam0Cdkn2aCdkn2atm4RdpKrasKrastm4TyjTgPdx1cre891Dam
• increased pancreatic ductal adenocarcinoma incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<+>,Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0009151I129C57BL6CBAFVBNCdkn2atm21RdpCdkn2aKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnTgPdx1cre891Dam0Cdkn2aTrp53tm1BrnKrasCdkn2atm21RdpTgPdx1cre891DamKrastm4Tyj
• increased metastatic potential_Cdkn2a<tm2.1Rdp>/Cdkn2a<+>,Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0001272I129C57BL6CBAFVBNCdkn2atm21RdpCdkn2aKrastm4TyjKrasTrp53tm1BrnTrp53TgPdx1cre891Dam0Trp53Cdkn2aKrasCdkn2atm21RdpTgPdx1cre891DamKrastm4TyjTrp53tm1Brn
• increased metastatic potential_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)89.1Dam/0
  http://metadb.riken.jp/0001272I129S4SvJaeC57BL6CBAFVBNKrastm4TyjKrasTgPdx1cre891Dam0Krastm4TyjTgPdx1cre891DamKras