Jee Young. An, et.al., Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103

http://rdf.ncbi.nlm.nih.gov/pubmed/16606826

Jee Young. An, et.al., Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal interatrial septum morphology_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0000282I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• abnormal heart development_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0000267I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• pale yolk sac_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0001722I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• abnormal blood vessel morphology_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0001614I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• disorganized myocardium_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0002190I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• embryonic growth arrest_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0001730I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• abnormal heart atrium morphology_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0003105I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• abnormal interventricular septum morphology_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0000281I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• abnormal forebrain development_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0003232I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• increased neural tube apoptosis_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0012505I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• abnormal vitelline vasculature morphology_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0003229I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• abnormal vitelline vascular remodeling_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0004076I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• hemorrhage_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0001914I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• abnormal heart morphology_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0000266I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• distended pericardium_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0000292I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• abnormal embryonic neuroepithelium morphology_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0004261I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• abnormal neuron differentiation_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0009937I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• kinked neural tube_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0003400I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• pericardial effusion_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0005312I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• embryonic lethality during organogenesis, complete penetrance_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0011098I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• abnormal myocardial trabeculae morphology_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0002189I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• decreased embryo size_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0001698I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• decreased embryonic neuroepithelium thickness_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0012703I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar
• abnormal heart ventricle morphology_Ubr1<tm1Avar>/Ubr1<tm1Avar>,Ubr2<tm1Ytkw>/Ubr2<tm1Ytkw>
  http://metadb.riken.jp/0005294I129S1SvC57BL6Ubr1tm1AvarUbr1tm1AvarUbr2tm1YtkwUbr2tm1YtkwUbr2tm1YtkwUbr1tm1Avar

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD00609
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00609