Scot J. Matkovich, et.al., Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling., Circulation research, 2006, 99

http://rdf.ncbi.nlm.nih.gov/pubmed/17008600

Scot J. Matkovich, et.al., Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling., Circulation research, 2006, 99

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Grk2<tm1Gwd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3763199
• Grk2<tm1.1Gwd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3763201

class

http://purl.org/net/cito/citesAsAuthority

• Grk2<tm1Gwd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3763199
• Grk2<tm1.1Gwd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3763201

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic growth arrest_Grk2<tm1.1Gwd>/Grk2<tm1.1Gwd>
  http://metadb.riken.jp/0001730I129S4SvJaeSorFVBNGrk2tm11GwdGrk2tm11GwdGrk2tm11Gwd
• abnormal heart tube morphology_Grk2<tm1.1Gwd>/Grk2<tm1.1Gwd>
  http://metadb.riken.jp/0000270I129S4SvJaeSorFVBNGrk2tm11GwdGrk2tm11GwdGrk2tm11Gwd
• pericardial edema_Grk2<tm1.1Gwd>/Grk2<tm1.1Gwd>
  http://metadb.riken.jp/0001787I129S4SvJaeSorFVBNGrk2tm11GwdGrk2tm11GwdGrk2tm11Gwd
• embryonic lethality during organogenesis, complete penetrance_Grk2<tm1.1Gwd>/Grk2<tm1.1Gwd>
  http://metadb.riken.jp/0011098I129S4SvJaeSorFVBNGrk2tm11GwdGrk2tm11GwdGrk2tm11Gwd
• decreased physiological sensitivity to xenobiotic_Grk2<tm1Gwd>/Grk2<tm1Gwd>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0008874I129S4SvJaeSor129S7SvEvBrdC57BL6Grk2tm1GwdGrk2tm1GwdNkx25tm1creRjsNkx25Nkx25Grk2tm1GwdNkx25tm1creRjs
• increased physiological sensitivity to xenobiotic_Grk2<tm1Gwd>/Grk2<tm1Gwd>,Nkx2-5<tm1(cre)Rjs>/Nkx2-5<+>
  http://metadb.riken.jp/0008873I129S4SvJaeSor129S7SvEvBrdC57BL6Grk2tm1GwdGrk2tm1GwdNkx25tm1creRjsNkx25Nkx25Grk2tm1GwdNkx25tm1creRjs
• no abnormal phenotype detected_Grk2<tm1Gwd>/Grk2<tm1Gwd>
  http://metadb.riken.jp/0002169I129S4SvJaeSorGrk2tm1GwdGrk2tm1GwdGrk2tm1Gwd
• embryonic growth retardation_Grk2<tm1.1Gwd>/Grk2<tm1.1Gwd>
  http://metadb.riken.jp/0003984I129S4SvJaeSorFVBNGrk2tm11GwdGrk2tm11GwdGrk2tm11Gwd