Terumasa. Okada, et.al., Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104

http://rdf.ncbi.nlm.nih.gov/pubmed/17416680

Terumasa. Okada, et.al., Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating glucose level_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005560I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgAlbcre21MgnInsrtm1Khn
• impaired glucose tolerance_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005293I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgIns2cre25Mgn0Insrtm1KhnTgIns2cre25Mgn
• increased sensitivity to induced morbidity/mortality_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009763I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgIns2cre25Mgn0Insrtm1KhnTgIns2cre25Mgn
• decreased pancreatic beta cell mass_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009114I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgIns2cre25Mgn0Insrtm1KhnTgIns2cre25Mgn
• decreased insulin secretion_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003059I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgIns2cre25Mgn0Insrtm1KhnTgIns2cre25Mgn
• polydipsia_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001426I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgIns2cre25Mgn0TgIns2cre25MgnInsrtm1KhnTgAlbcre21Mgn
• premature death_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgIns2cre25Mgn0TgIns2cre25MgnInsrtm1KhnTgAlbcre21Mgn
• hyperglycemia_Igf1r<tm1.1Mhz>/Igf1r<tm1.1Mhz>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001559I129SvC57BL6DBA2Igf1rtm11MhzIgf1rtm11MhzTgIns2cre25Mgn0Igf1rtm11MhzTgIns2cre25Mgn
• polyuria_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001762I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgIns2cre25Mgn0TgIns2cre25MgnInsrtm1KhnTgAlbcre21Mgn
• increased circulating insulin level_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0002079I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgIns2cre25Mgn0TgIns2cre25MgnInsrtm1KhnTgAlbcre21Mgn
• increased circulating insulin level_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002079I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgAlbcre21MgnInsrtm1Khn
• decreased insulin secretion_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003059I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgIns2cre25Mgn0TgIns2cre25MgnInsrtm1KhnTgAlbcre21Mgn
• impaired glucose tolerance_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005293I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgAlbcre21MgnInsrtm1Khn
• hyperglycemia_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0001559I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgAlbcre21MgnInsrtm1Khn
• premature death_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgIns2cre25Mgn0Insrtm1KhnTgIns2cre25Mgn
• impaired glucose tolerance_Igf1r<tm1.1Mhz>/Igf1r<tm1.1Mhz>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005293I129SvC57BL6DBA2Igf1rtm11MhzIgf1rtm11MhzTgIns2cre25Mgn0Igf1rtm11MhzTgIns2cre25Mgn
• insulin resistance_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005331I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgAlbcre21MgnInsrtm1Khn
• increased pancreatic beta cell mass_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0009113I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgAlbcre21MgnInsrtm1Khn
• decreased body weight_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001262I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgIns2cre25Mgn0TgIns2cre25MgnInsrtm1KhnTgAlbcre21Mgn
• hyperglycemia_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001559I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgIns2cre25Mgn0TgIns2cre25MgnInsrtm1KhnTgAlbcre21Mgn
• hyperglycemia_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001559I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgIns2cre25Mgn0Insrtm1KhnTgIns2cre25Mgn
• insulin resistance_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005331I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgIns2cre25Mgn0TgIns2cre25MgnInsrtm1KhnTgAlbcre21Mgn
• impaired glucose tolerance_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005293I129S4SvJaeC57BL6DBA2Insrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgIns2cre25Mgn0TgIns2cre25MgnInsrtm1KhnTgAlbcre21Mgn