Lynsey. Meikle, et.al., A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/17522300

Lynsey. Meikle, et.al., A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, 27

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal dentate gyrus morphology_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0000812I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• tremors_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0000745I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• abnormal neuron morphology_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0002882I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• abnormal cerebral cortex morphology_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0000788I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• slow postnatal weight gain_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0008489I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• abnormal body size_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0003956I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm1DjkTgSyn1cre671Jxm0Tsc1tm1DjkTgSyn1cre671Jxm
• premature death_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• premature death_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm1DjkTgSyn1cre671Jxm0Tsc1tm1DjkTgSyn1cre671Jxm
• sporadic seizures_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0000951I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• increased startle reflex_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0001488I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• abnormal brain wave pattern_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0004994I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• abnormal behavior_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0004924I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm1DjkTgSyn1cre671Jxm0Tsc1tm1DjkTgSyn1cre671Jxm
• limb grasping_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0001513I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• abnormal myelination_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0000920I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• straub tail_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0003382I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• abnormal hippocampus region morphology_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0008262I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• abnormal limb posture_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0004263I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• hypoactivity_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0001402I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• abnormal brain morphology_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0002152I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• abnormal neocortex morphology_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0008547I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• abnormal nervous system morphology_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0003632I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm1DjkTgSyn1cre671Jxm0Tsc1tm1DjkTgSyn1cre671Jxm
• abnormal neuron differentiation_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0009937I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• hunched posture_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0001505I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• seizures_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0002064I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• abnormal nervous system physiology_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0003633I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm1DjkTgSyn1cre671Jxm0Tsc1tm1DjkTgSyn1cre671Jxm
• hyperactivity_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0001399I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm
• abnormal hippocampus pyramidal cell layer_Tsc1<tm1Djk>/Tsc1<tm1.1Djk>,Tg(Syn1-cre)671Jxm/0
  http://metadb.riken.jp/0008284I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm0Tsc1tm1DjkTsc1tm11DjkTgSyn1cre671Jxm