Rusty L. Montgomery, et.al., Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility., Genes & development, 2007, 21

http://rdf.ncbi.nlm.nih.gov/pubmed/17639084

Rusty L. Montgomery, et.al., Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility., Genes & development, 2007, 21

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Hdac1<tm1.1Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717923
• Hdac1<tm1.2Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717925
• Hdac2<tm1.1Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717927
• Hdac2<tm1.2Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717930

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• cyanosis_Hdac2<tm1.2Eno>/Hdac2<tm1.2Eno>
  http://metadb.riken.jp/0001575I129SSvEvC57BL6CD1Hdac2tm12EnoHdac2tm12EnoHdac2tm12Eno
• irregular heartbeat_Hdac1<tm1.1Eno>/Hdac1<tm1.1Eno>,Hdac2<tm1.1Eno>/Hdac2<tm1.1Eno>,Tg(Myh6-cre)2182Mds/?
  http://metadb.riken.jp/0001636I129SSvEvC57BL6CD1FVBNHdac1tm11EnoHdac1tm11EnoHdac2tm11EnoHdac2tm11EnoTgMyh6cre2182MdsHdac1tm11EnoHdac2tm11EnoTgMyh6cre2182Mds
• no abnormal phenotype detected_Hdac1<tm1.1Eno>/Hdac1<tm1.1Eno>,Tg(Myh6-cre)2182Mds/?
  http://metadb.riken.jp/0002169I129SSvEvC57BL6CD1FVBNHdac1tm11EnoHdac1tm11EnoTgMyh6cre2182MdsHdac1tm11EnoTgMyh6cre2182Mds
• no abnormal phenotype detected_Hdac2<tm1.1Eno>/Hdac2<tm1.1Eno>,Tg(Myh6-cre)2182Mds/?
  http://metadb.riken.jp/0002169I129SSvEvC57BL6CD1FVBNHdac2tm11EnoHdac2tm11EnoTgMyh6cre2182MdsTgMyh6cre2182MdsHdac2tm11Eno
• increased cardiomyocyte apoptosis_Hdac1<tm1.1Eno>/Hdac1<tm1.1Eno>,Hdac2<tm1.1Eno>/Hdac2<tm1.1Eno>,Tg(Myh6-cre)2182Mds/?
  http://metadb.riken.jp/0003222I129SSvEvC57BL6CD1FVBNHdac1tm11EnoHdac1tm11EnoHdac2tm11EnoHdac2tm11EnoTgMyh6cre2182MdsHdac1tm11EnoHdac2tm11EnoTgMyh6cre2182Mds
• increased cardiomyocyte apoptosis_Hdac2<tm1.2Eno>/Hdac2<tm1.2Eno>
  http://metadb.riken.jp/0003222I129SSvEvC57BL6CD1Hdac2tm12EnoHdac2tm12EnoHdac2tm12Eno
他8件を見る
• abnormal fetal cardiomyocyte proliferation_Hdac2<tm1.2Eno>/Hdac2<tm1.2Eno>
  http://metadb.riken.jp/0003567I129SSvEvC57BL6CD1Hdac2tm12EnoHdac2tm12EnoHdac2tm12Eno
• abnormal heart right ventricle morphology_Hdac2<tm1.2Eno>/Hdac2<tm1.2Eno>
  http://metadb.riken.jp/0003920I129SSvEvC57BL6CD1Hdac2tm12EnoHdac2tm12EnoHdac2tm12Eno
• decreased heart rate_Hdac2<tm1.2Eno>/Hdac2<tm1.2Eno>
  http://metadb.riken.jp/0005333I129SSvEvC57BL6CD1Hdac2tm12EnoHdac2tm12EnoHdac2tm12Eno
• dilated heart ventricle_Hdac1<tm1.1Eno>/Hdac1<tm1.1Eno>,Hdac2<tm1.1Eno>/Hdac2<tm1.1Eno>,Tg(Myh6-cre)2182Mds/?
  http://metadb.riken.jp/0008022I129SSvEvC57BL6CD1FVBNHdac1tm11EnoHdac1tm11EnoHdac2tm11EnoHdac2tm11EnoTgMyh6cre2182MdsHdac1tm11EnoHdac2tm11EnoTgMyh6cre2182Mds
• thick interventricular septum_Hdac2<tm1.2Eno>/Hdac2<tm1.2Eno>
  http://metadb.riken.jp/0010724I129SSvEvC57BL6CD1Hdac2tm12EnoHdac2tm12EnoHdac2tm12Eno
• postnatal lethality, incomplete penetrance_Hdac1<tm1.1Eno>/Hdac1<tm1.1Eno>,Hdac2<tm1.1Eno>/Hdac2<tm1.1Eno>,Tg(Myh6-cre)2182Mds/?
  http://metadb.riken.jp/0011086I129SSvEvC57BL6CD1FVBNHdac1tm11EnoHdac1tm11EnoHdac2tm11EnoHdac2tm11EnoTgMyh6cre2182MdsHdac1tm11EnoHdac2tm11EnoTgMyh6cre2182Mds
• neonatal lethality, complete penetrance_Hdac2<tm1.2Eno>/Hdac2<tm1.2Eno>
  http://metadb.riken.jp/0011087I129SSvEvC57BL6CD1Hdac2tm12EnoHdac2tm12EnoHdac2tm12Eno
• embryonic lethality, complete penetrance_Hdac1<tm1.2Eno>/Hdac1<tm1.2Eno>
  http://metadb.riken.jp/0011092I129SSvEvC57BL6CD1Hdac1tm12EnoHdac1tm12EnoHdac1tm12Eno

class

http://purl.org/net/cito/citesAsAuthority

• Hdac1<tm1.1Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717923
• Hdac1<tm1.2Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717925
• Hdac2<tm1.1Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717927
• Hdac2<tm1.2Eno>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717930