Yangu. Zhao, et.al., LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104

http://rdf.ncbi.nlm.nih.gov/pubmed/17664423

Yangu. Zhao, et.al., LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lhx1<tm4Bhr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3719681
• Ldb1<tm2Lmgd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3719683

class

http://purl.org/net/cito/citesAsAuthority

• Lhx1<tm4Bhr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3719681
• Ldb1<tm2Lmgd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3719683

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• absent Purkinje cell layer_Lhx1<tm1Tmj>/Lhx1<tm4Bhr>,Lhx5<tm1Lmgd>/Lhx5<tm1Lmgd>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009718I129S1Sv129X1SvJC57BL6SJLLhx1tm1TmjLhx1tm4BhrLhx5tm1LmgdLhx5tm1LmgdTgNescre1Kln0TgNescre1KlnLhx1tm1TmjLhx1tm4BhrLhx5tm1Lmgd
• small cerebellum_Lhx1<tm1Tmj>/Lhx1<tm4Bhr>,Lhx5<tm1Lmgd>/Lhx5<tm1Lmgd>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000852I129S1Sv129X1SvJC57BL6SJLLhx1tm1TmjLhx1tm4BhrLhx5tm1LmgdLhx5tm1LmgdTgNescre1Kln0TgNescre1KlnLhx1tm1TmjLhx1tm4BhrLhx5tm1Lmgd
• small cerebellum_Ldb1<tm2Lmgd>/Ldb1<tm2Lmgd>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000852IC57BL6FVBNSJLLdb1tm2LmgdLdb1tm2LmgdTgNescre1Kln0Ldb1tm2LmgdTgNescre1Kln
• decreased Purkinje cell number_En1<tm2(cre)Wrst>/En1<+>,Lhx1<tm1Tmj>/Lhx1<tm2.1Bhr>,Lhx5<tm1Lmgd>/Lhx5<tm1Lmgd>
  http://metadb.riken.jp/0000880I129S1Sv129S7SvEvBrd129X1SvJEn1tm2creWrstEn1Lhx1tm1TmjLhx1tm21BhrLhx5tm1LmgdLhx5tm1LmgdEn1Lhx5tm1LmgdEn1tm2creWrstLhx1tm21BhrLhx1tm1Tmj
• small cerebellum_En1<tm2(cre)Wrst>/En1<+>,Lhx1<tm1Tmj>/Lhx1<tm2.1Bhr>,Lhx5<tm1Lmgd>/Lhx5<tm1Lmgd>
  http://metadb.riken.jp/0000852I129S1Sv129S7SvEvBrd129X1SvJEn1tm2creWrstEn1Lhx1tm1TmjLhx1tm21BhrLhx5tm1LmgdLhx5tm1LmgdEn1Lhx5tm1LmgdEn1tm2creWrstLhx1tm21BhrLhx1tm1Tmj
• decreased Purkinje cell number_Ldb1<tm2Lmgd>/Ldb1<tm2Lmgd>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000880IC57BL6FVBNSJLLdb1tm2LmgdLdb1tm2LmgdTgNescre1Kln0Ldb1tm2LmgdTgNescre1Kln
• absent Purkinje cell layer_En1<tm2(cre)Wrst>/En1<+>,Lhx1<tm1Tmj>/Lhx1<tm2.1Bhr>,Lhx5<tm1Lmgd>/Lhx5<tm1Lmgd>
  http://metadb.riken.jp/0009718I129S1Sv129S7SvEvBrd129X1SvJEn1tm2creWrstEn1Lhx1tm1TmjLhx1tm21BhrLhx5tm1LmgdLhx5tm1LmgdEn1Lhx5tm1LmgdEn1tm2creWrstLhx1tm21BhrLhx1tm1Tmj
• decreased Purkinje cell number_Lhx1<tm1Tmj>/Lhx1<tm4Bhr>,Lhx5<tm1Lmgd>/Lhx5<tm1Lmgd>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000880I129S1Sv129X1SvJC57BL6SJLLhx1tm1TmjLhx1tm4BhrLhx5tm1LmgdLhx5tm1LmgdTgNescre1Kln0TgNescre1KlnLhx1tm1TmjLhx1tm4BhrLhx5tm1Lmgd
• absent cerebellar foliation_Ldb1<tm2Lmgd>/Ldb1<tm2Lmgd>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000853IC57BL6FVBNSJLLdb1tm2LmgdLdb1tm2LmgdTgNescre1Kln0Ldb1tm2LmgdTgNescre1Kln
• neonatal lethality, complete penetrance_Lhx1<tm4Bhr>/Lhx1<tm4Bhr>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0011087I129S1Sv129X1SvJC57BL6SJLLhx1tm4BhrLhx1tm4BhrTgNescre1Kln0TgNescre1KlnLhx1tm4Bhr
• absent cerebellar foliation_Lhx1<tm1Tmj>/Lhx1<tm4Bhr>,Lhx5<tm1Lmgd>/Lhx5<tm1Lmgd>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000853I129S1Sv129X1SvJC57BL6SJLLhx1tm1TmjLhx1tm4BhrLhx5tm1LmgdLhx5tm1LmgdTgNescre1Kln0TgNescre1KlnLhx1tm1TmjLhx1tm4BhrLhx5tm1Lmgd
• no abnormal phenotype detected_En1<tm2(cre)Wrst>/En1<+>,Lhx1<tm2.1Bhr>/Lhx1<tm2.1Bhr>
  http://metadb.riken.jp/0002169I129S1Sv129S7SvEvBrd129X1SvJEn1tm2creWrstEn1Lhx1tm21BhrLhx1tm21BhrLhx1tm21BhrEn1tm2creWrstEn1