Keisuke. Horiuchi, et.al., Cutting edge: TNF-alpha-converting enzyme (TACE/ADAM17) inactivation in mouse myeloid cells prevents lethality from endotoxin shock., Journal of immunology (Baltimore, Md. : 1950), 2007, 179

http://rdf.ncbi.nlm.nih.gov/pubmed/17709479

Keisuke. Horiuchi, et.al., Cutting edge: TNF-alpha-converting enzyme (TACE/ADAM17) inactivation in mouse myeloid cells prevents lethality from endotoxin shock., Journal of immunology (Baltimore, Md. : 1950), 2007, 179

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Adam17<tm1Bbl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3713365
• Adam17<tm1.1Bbl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3713366
• Adam17<tm1.2Bbl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4354847

class

http://purl.org/net/cito/citesAsAuthority

• Adam17<tm1Bbl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3713365
• Adam17<tm1.1Bbl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3713366
• Adam17<tm1.2Bbl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4354847

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• eyelids open at birth_Adam17<tm1.1Bbl>/Adam17<tm1.1Bbl>
  http://metadb.riken.jp/0001302I129P2OlaHsdFVBNAdam17tm11BblAdam17tm11BblAdam17tm11Bbl
• no abnormal phenotype detected_Adam17<tm1Bbl>/Adam17<tm1Bbl>
  http://metadb.riken.jp/0002169I129P2OlaHsdAdam17tm1BblAdam17tm1BblAdam17tm1Bbl
• no abnormal phenotype detected_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>
  http://metadb.riken.jp/0002169I129P2OlaHsdC57BL6Adam17tm12BblAdam17tm12BblAdam17tm12Bbl
• abnormal macrophage physiology_Adam17<tm1Bbl>/Adam17<tm1Bbl>,Lyz2<tm1(cre)Ifo>/0
  http://metadb.riken.jp/0002451I129P2OlaHsdAdam17tm1BblAdam17tm1BblLyz2tm1creIfo0Lyz2tm1creIfoAdam17tm1Bbl
• abnormal tricuspid valve morphology_Adam17<tm1.1Bbl>/Adam17<tm1.1Bbl>
  http://metadb.riken.jp/0002624I129P2OlaHsdFVBNAdam17tm11BblAdam17tm11BblAdam17tm11Bbl
• abnormal aortic valve morphology_Adam17<tm1.1Bbl>/Adam17<tm1.1Bbl>
  http://metadb.riken.jp/0002747I129P2OlaHsdFVBNAdam17tm11BblAdam17tm11BblAdam17tm11Bbl
他6件を見る
• abnormal pulmonary valve morphology_Adam17<tm1.1Bbl>/Adam17<tm1.1Bbl>
  http://metadb.riken.jp/0002748I129P2OlaHsdFVBNAdam17tm11BblAdam17tm11BblAdam17tm11Bbl
• decreased circulating tumor necrosis factor level_Adam17<tm1Bbl>/Adam17<tm1Bbl>,Lyz2<tm1(cre)Ifo>/0
  http://metadb.riken.jp/0008554I129P2OlaHsdAdam17tm1BblAdam17tm1BblLyz2tm1creIfo0Lyz2tm1creIfoAdam17tm1Bbl
• decreased circulating tumor necrosis factor level_Adam17<tm1Bbl>/Adam17<tm1Bbl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008554I129P2OlaHsdC57BL6CBAAdam17tm1BblAdam17tm1BblTgMx1cre1Cgn0TgMx1cre1CgnAdam17tm1Bbl
• decreased susceptibility to endotoxin shock_Adam17<tm1Bbl>/Adam17<tm1Bbl>,Lyz2<tm1(cre)Ifo>/0
  http://metadb.riken.jp/0008734I129P2OlaHsdAdam17tm1BblAdam17tm1BblLyz2tm1creIfo0Lyz2tm1creIfoAdam17tm1Bbl
• decreased susceptibility to endotoxin shock_Adam17<tm1Bbl>/Adam17<tm1Bbl>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0008734I129P2OlaHsdC57BL6CBAAdam17tm1BblAdam17tm1BblTgMx1cre1Cgn0TgMx1cre1CgnAdam17tm1Bbl
• postnatal lethality, complete penetrance_Adam17<tm1.1Bbl>/Adam17<tm1.1Bbl>
  http://metadb.riken.jp/0011085I129P2OlaHsdFVBNAdam17tm11BblAdam17tm11BblAdam17tm11Bbl