Diana I. Albu, et.al., BCL11B is required for positive selection and survival of double-positive thymocytes., The Journal of experimental medicine, 2007, 204

http://rdf.ncbi.nlm.nih.gov/pubmed/17998389

Diana I. Albu, et.al., BCL11B is required for positive selection and survival of double-positive thymocytes., The Journal of experimental medicine, 2007, 204

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Bcl11b<tm1Avram>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3767620

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• thymus hypoplasia_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tcra<tm1Mom>/Tcra<tm1Mom>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0001823I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTcratm1MomTcratm1MomTgCd4cre1CwiBcl11btm1AvramTgCd4cre1CwiTcratm1Mom
• enlarged mesenteric lymph nodes_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0008466I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• spleen hyperplasia_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0000693I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• decreased double-positive T cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0005092I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• increased spleen weight_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0004952I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• abnormal positive T cell selection_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tcra<tm1Mom>/Tcra<tm1Mom>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0004919I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTcratm1MomTcratm1MomTgCd4cre1CwiBcl11btm1AvramTgCd4cre1CwiTcratm1Mom
• increased B cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0005014I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• thymus hypoplasia_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0001823I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• increased NK cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0008044I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• decreased double-positive T cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?,Tg(LCKprBCL2)36Sjk/?
  http://metadb.riken.jp/0005092I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgLCKprBCL236SjkBcl11btm1AvramTgLCKprBCL236SjkTgCd4cre1Cwi
• abnormal leukocyte morphology_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0008246I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• decreased CD8-positive, alpha-beta T cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?,Tg(LCKprBCL2)36Sjk/?
  http://metadb.riken.jp/0008079I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgLCKprBCL236SjkBcl11btm1AvramTgLCKprBCL236SjkTgCd4cre1Cwi
• decreased CD8-positive, alpha-beta T cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0008079I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• decreased double-negative T cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0005089I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• abnormal positive T cell selection_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0004919I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• abnormal positive T cell selection_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?,Tg(LCKprBCL2)36Sjk/?
  http://metadb.riken.jp/0004919I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgLCKprBCL236SjkBcl11btm1AvramTgLCKprBCL236SjkTgCd4cre1Cwi
• thymus hypoplasia_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?,Tg(LCKprBCL2)36Sjk/?
  http://metadb.riken.jp/0001823I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgLCKprBCL236SjkBcl11btm1AvramTgLCKprBCL236SjkTgCd4cre1Cwi
• decreased CD4-positive, alpha beta T cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?,Tg(LCKprBCL2)36Sjk/?
  http://metadb.riken.jp/0008075I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgLCKprBCL236SjkBcl11btm1AvramTgLCKprBCL236SjkTgCd4cre1Cwi
• decreased double-positive T cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tcra<tm1Mom>/Tcra<tm1Mom>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0005092I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTcratm1MomTcratm1MomTgCd4cre1CwiBcl11btm1AvramTgCd4cre1CwiTcratm1Mom
• abnormal thymocyte activation_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0003850I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• increased dendritic cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0008126I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• decreased CD4-positive, alpha beta T cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0008075I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram
• increased gamma-delta T cell number_Bcl11b<tm1Avram>/Bcl11b<tm1Avram>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0008346I129C57BL6DBA2Bcl11btm1AvramBcl11btm1AvramTgCd4cre1CwiTgCd4cre1CwiBcl11btm1Avram

class

http://purl.org/net/cito/citesAsAuthority

• Bcl11b<tm1Avram>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3767620