Nanda A. Singh, et.al., Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization., The Journal of physiology, 2008, 586

http://rdf.ncbi.nlm.nih.gov/pubmed/18483067

Nanda A. Singh, et.al., Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization., The Journal of physiology, 2008, 586

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4397593
• Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4397592

class

http://purl.org/net/cito/citesAsAuthority

• Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4397593
• Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4397592

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• prenatal lethality, incomplete penetrance_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0011101I129S1Sv129X1SvJFVBNKcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas
• seizures_Kcnq2<tm1.1Naas>/Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/0002064I129S1Sv129X1SvJC57BL6Kcnq2tm11NaasKcnq2tm11NaasKcnq2tm11Naas
• neonatal lethality, incomplete penetrance_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0011088FVB129Kcnq3tm11NaasKcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas
• seizures_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0002064I129S1Sv129X1SvJC57BL6Kcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas
• decreased body size_Kcnq2<tm1.1Naas>/Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/0001265FVB129Kcnq2tm11NaasKcnq2tm11NaasKcnq2tm11NaasKcnq2tm11Naas
• tonic-clonic seizures_Kcnq2<tm1.1Naas>/Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/0003997B6129Kcnq2tm11NaasKcnq2tm11NaasKcnq2tm11NaasKcnq2tm11Naas
• prenatal lethality, incomplete penetrance_Kcnq2<tm1.1Naas>/Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/0011101FVB129Kcnq2tm11NaasKcnq2tm11NaasKcnq2tm11NaasKcnq2tm11Naas
• prenatal lethality, incomplete penetrance_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0011101I129S1Sv129X1SvJC57BL6Kcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas
• abnormal neuron physiology_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0004811I129S1Sv129X1SvJC57BL6Kcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas
• prenatal lethality, incomplete penetrance_Kcnq2<tm1.1Naas>/Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/0011101I129S1Sv129X1SvJC57BL6Kcnq2tm11NaasKcnq2tm11NaasKcnq2tm11Naas
• abnormal neuron physiology_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0004811I129S1Sv129X1SvJFVBNKcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas
• premature death_Kcnq2<tm1.1Naas>/Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/0002083B6129Kcnq2tm11NaasKcnq2tm11NaasKcnq2tm11NaasKcnq2tm11Naas
• abnormal neuron physiology_Kcnq2<tm1.1Naas>/Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/0004811I129S1Sv129X1SvJC57BL6Kcnq2tm11NaasKcnq2tm11NaasKcnq2tm11Naas
• decreased body size_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0001265FVB129Kcnq3tm11NaasKcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas
• seizures_Kcnq2<tm1.1Naas>/Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/0002064FVB129Kcnq2tm11NaasKcnq2tm11NaasKcnq2tm11NaasKcnq2tm11Naas
• abnormal seizure response to electrical stimulation_Kcnq3<tm1.1Naas>/Kcnq3<+>
  http://metadb.riken.jp/0001650I129S1Sv129X1SvJFVBNKcnq3tm11NaasKcnq3Kcnq3tm11NaasKcnq3
• neonatal lethality, incomplete penetrance_Kcnq2<tm1.1Naas>/Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/0011088B6129Kcnq2tm11NaasKcnq2tm11NaasKcnq2tm11NaasKcnq2tm11Naas
• prenatal lethality, incomplete penetrance_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0011101B6129Kcnq3tm11NaasKcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas
• astrocytosis_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0003354FVB129Kcnq3tm11NaasKcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas
• decreased body size_Kcnq2<tm1.1Naas>/Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/0001265B6129Kcnq2tm11NaasKcnq2tm11NaasKcnq2tm11NaasKcnq2tm11Naas
• abnormal seizure response to electrical stimulation_Kcnq2<tm1.1Naas>/Kcnq2<+>
  http://metadb.riken.jp/0001650I129S1Sv129X1SvJC57BL6Kcnq2tm11NaasKcnq2Kcnq2tm11NaasKcnq2
• postnatal lethality, incomplete penetrance_Kcnq2<tm1.1Naas>/Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/0011086FVB129Kcnq2tm11NaasKcnq2tm11NaasKcnq2tm11NaasKcnq2tm11Naas
• premature death_Kcnq2<tm1.1Naas>/Kcnq2<tm1.1Naas>
  http://metadb.riken.jp/0002083FVB129Kcnq2tm11NaasKcnq2tm11NaasKcnq2tm11NaasKcnq2tm11Naas
• premature death_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0002083FVB129Kcnq3tm11NaasKcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas
• decreased body size_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0001265B6129Kcnq3tm11NaasKcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas
• abnormal seizure response to electrical stimulation_Kcnq3<tm1.1Naas>/Kcnq3<+>
  http://metadb.riken.jp/0001650I129S1Sv129X1SvJC57BL6Kcnq3tm11NaasKcnq3Kcnq3tm11NaasKcnq3
• abnormal hippocampus morphology_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0000807FVB129Kcnq3tm11NaasKcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas
• seizures_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0002064B6129Kcnq3tm11NaasKcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas
• seizures_Kcnq3<tm1.1Naas>/Kcnq3<tm1.1Naas>
  http://metadb.riken.jp/0002064FVB129Kcnq3tm11NaasKcnq3tm11NaasKcnq3tm11NaasKcnq3tm11Naas

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD11014
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD11014
• CD46405
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD46405