Kwon-Ho. Hong, et.al., Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension., Circulation, 2008, 118

http://rdf.ncbi.nlm.nih.gov/pubmed/18663089

Kwon-Ho. Hong, et.al., Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension., Circulation, 2008, 118

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Acvrl1-cre)B1Spo
  http://metadb.riken.jp/db/mgi_rdf/MGI:4438606

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Acvrl1-cre)B1Spo
  http://metadb.riken.jp/db/mgi_rdf/MGI:4438606

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal thrombosis_Bmpr2<tm1.1Enl>/Bmpr2<tm1.1Enl>,Tg(Acvrl1-cre)L1Spo/0
  http://metadb.riken.jp/0005048I129S4SvJaeFVBBmpr2tm11EnlBmpr2tm11EnlTgAcvrl1creL1Spo0TgAcvrl1creL1SpoBmpr2tm11Enl
• abnormal vascular smooth muscle physiology_Bmpr2<tm1.1Enl>/Bmpr2<tm1.1Enl>,Tg(Acvrl1-cre)L1Spo/0
  http://metadb.riken.jp/0005595I129S4SvJaeFVBBmpr2tm11EnlBmpr2tm11EnlTgAcvrl1creL1Spo0TgAcvrl1creL1SpoBmpr2tm11Enl
• increased lung endothelial cell proliferation_Bmpr2<tm1.1Enl>/Bmpr2<tm1.1Enl>,Tg(Acvrl1-cre)L1Spo/0
  http://metadb.riken.jp/0011139I129S4SvJaeFVBBmpr2tm11EnlBmpr2tm11EnlTgAcvrl1creL1Spo0TgAcvrl1creL1SpoBmpr2tm11Enl
• abnormal pulmonary artery morphology_Bmpr2<tm1.1Enl>/Bmpr2<tm1.1Enl>,Tg(Acvrl1-cre)L1Spo/0
  http://metadb.riken.jp/0000484I129S4SvJaeFVBBmpr2tm11EnlBmpr2tm11EnlTgAcvrl1creL1Spo0TgAcvrl1creL1SpoBmpr2tm11Enl
• artery occlusion_Bmpr2<tm1.1Enl>/Bmpr2<tm1.1Enl>,Tg(Acvrl1-cre)L1Spo/0
  http://metadb.riken.jp/0006134I129S4SvJaeFVBBmpr2tm11EnlBmpr2tm11EnlTgAcvrl1creL1Spo0TgAcvrl1creL1SpoBmpr2tm11Enl
• abnormal lung vasculature morphology_Bmpr2<tm1.1Enl>/Bmpr2<tm1.1Enl>,Tg(Acvrl1-cre)L1Spo/0
  http://metadb.riken.jp/0004007I129S4SvJaeFVBBmpr2tm11EnlBmpr2tm11EnlTgAcvrl1creL1Spo0TgAcvrl1creL1SpoBmpr2tm11Enl
• heart right ventricle hypertrophy_Bmpr2<tm1.1Enl>/Bmpr2<tm1.1Enl>,Tg(Acvrl1-cre)L1Spo/0
  http://metadb.riken.jp/0000276I129S4SvJaeFVBBmpr2tm11EnlBmpr2tm11EnlTgAcvrl1creL1Spo0TgAcvrl1creL1SpoBmpr2tm11Enl
• pulmonary hypertension_Bmpr2<tm1.1Enl>/Bmpr2<tm1.1Enl>,Tg(Acvrl1-cre)L1Spo/0
  http://metadb.riken.jp/0003548I129S4SvJaeFVBBmpr2tm11EnlBmpr2tm11EnlTgAcvrl1creL1Spo0TgAcvrl1creL1SpoBmpr2tm11Enl
• increased pulmonary artery pressure_Bmpr2<tm1.1Enl>/Bmpr2<tm1.1Enl>,Tg(Acvrl1-cre)L1Spo/0
  http://metadb.riken.jp/0004012I129S4SvJaeFVBBmpr2tm11EnlBmpr2tm11EnlTgAcvrl1creL1Spo0TgAcvrl1creL1SpoBmpr2tm11Enl