Maria. Kauppi, et.al., Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice., Blood, 2008, 112

http://rdf.ncbi.nlm.nih.gov/pubmed/18684867

Maria. Kauppi, et.al., Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice., Blood, 2008, 112

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ep300<Plt6>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3813243

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased leukocyte cell number_Ep300<Plt6>/Ep300<Plt6>
  http://metadb.riken.jp/0000221I129S1SvC57BL6Ep300Plt6Ep300Plt6Ep300Plt6
• increased eosinophil cell number_Ep300<Plt6>/Ep300<+>,Mpl<tm1Wsa>/Mpl<tm1Wsa>
  http://metadb.riken.jp/0005011I129S1SvC57BL6Ep300Plt6Ep300Mpltm1WsaMpltm1WsaEp300Mpltm1WsaEp300Plt6
• postnatal lethality_Ep300<Plt6>/Ep300<Plt6>
  http://metadb.riken.jp/0002082I129S1SvC57BL6Ep300Plt6Ep300Plt6Ep300Plt6
• abnormal megakaryocyte progenitor cell morphology_Ep300<Plt6>/Ep300<+>,Mpl<tm1Wsa>/Mpl<tm1Wsa>
  http://metadb.riken.jp/0002413I129S1SvC57BL6Ep300Plt6Ep300Mpltm1WsaMpltm1WsaEp300Mpltm1WsaEp300Plt6
• decreased lymphocyte cell number_Ep300<Plt6>/Ep300<Plt6>
  http://metadb.riken.jp/0005016I129S1SvC57BL6Ep300Plt6Ep300Plt6Ep300Plt6
• thrombocytosis_Ep300<Plt6>/Ep300<Plt6>
  http://metadb.riken.jp/0005505I129S1SvC57BL6Ep300Plt6Ep300Plt6Ep300Plt6
• decreased B cell number_Ep300<Plt6>/Ep300<Plt6>
  http://metadb.riken.jp/0005017I129S1SvC57BL6Ep300Plt6Ep300Plt6Ep300Plt6
• thrombocytosis_Ep300<Plt6>/Ep300<Plt6>,Mpl<tm1Wsa>/Mpl<tm1Wsa>
  http://metadb.riken.jp/0005505I129S1SvC57BL6Ep300Plt6Ep300Plt6Mpltm1WsaMpltm1WsaMpltm1WsaEp300Plt6
• postnatal lethality_Ep300<Plt6>/Ep300<Plt6>,Mpl<tm1Wsa>/Mpl<tm1Wsa>
  http://metadb.riken.jp/0002082I129S1SvC57BL6Ep300Plt6Ep300Plt6Mpltm1WsaMpltm1WsaMpltm1WsaEp300Plt6
• increased megakaryocyte cell number_Ep300<Plt6>/Ep300<Plt6>,Mpl<tm1Wsa>/Mpl<tm1Wsa>
  http://metadb.riken.jp/0008254I129S1SvC57BL6Ep300Plt6Ep300Plt6Mpltm1WsaMpltm1WsaMpltm1WsaEp300Plt6
• increased megakaryocyte cell number_Ep300<Plt6>/Ep300<+>,Mpl<tm1Wsa>/Mpl<tm1Wsa>
  http://metadb.riken.jp/0008254I129S1SvC57BL6Ep300Plt6Ep300Mpltm1WsaMpltm1WsaEp300Mpltm1WsaEp300Plt6
• abnormal platelet morphology_Ep300<Plt6>/Ep300<+>,Mpl<tm1Wsa>/Mpl<tm1Wsa>
  http://metadb.riken.jp/0004720I129S1SvC57BL6Ep300Plt6Ep300Mpltm1WsaMpltm1WsaEp300Mpltm1WsaEp300Plt6
• abnormal megakaryocyte progenitor cell morphology_Ep300<Plt6>/Ep300<Plt6>,Mpl<tm1Wsa>/Mpl<tm1Wsa>
  http://metadb.riken.jp/0002413I129S1SvC57BL6Ep300Plt6Ep300Plt6Mpltm1WsaMpltm1WsaMpltm1WsaEp300Plt6
• decreased eosinophil cell number_Ep300<Plt6>/Ep300<Plt6>
  http://metadb.riken.jp/0005012I129S1SvC57BL6Ep300Plt6Ep300Plt6Ep300Plt6

class

http://purl.org/net/cito/citesAsAuthority

• Ep300<Plt6>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3813243