Katerina V. Savelieva, et.al., Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants., PloS one, 2008, 3

http://rdf.ncbi.nlm.nih.gov/pubmed/18923670

Katerina V. Savelieva, et.al., Genetic disruption of both tryptophan hydroxylase genes dramatically reduces serotonin and affects behavior in models sensitive to antidepressants., PloS one, 2008, 3

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tph2<tm1Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3831654
• Tph1<tm2Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3831653

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased thermal nociceptive threshold_Tph1<tm2Lex>/Tph1<tm2Lex>,Tph2<tm1Lex>/Tph2<tm1Lex>
  http://metadb.riken.jp/0003998I129S5SvEvBrdC57BL6JTph1tm2LexTph1tm2LexTph2tm1LexTph2tm1LexTph1tm2LexTph2tm1Lex
• decreased percent body fat/body weight_Tph1<tm2Lex>/Tph1<tm2Lex>,Tph2<tm1Lex>/Tph2<tm1Lex>
  http://metadb.riken.jp/0005459I129S5SvEvBrdC57BL6JTph1tm2LexTph1tm2LexTph2tm1LexTph2tm1LexTph1tm2LexTph2tm1Lex
• decreased body length_Tph2<tm1Lex>/Tph2<tm1Lex>
  http://metadb.riken.jp/0001258I129S5SvEvBrdC57BL6JTph2tm1LexTph2tm1LexTph2tm1Lex
• decreased body length_Tph1<tm2Lex>/Tph1<tm2Lex>,Tph2<tm1Lex>/Tph2<tm1Lex>
  http://metadb.riken.jp/0001258I129S5SvEvBrdC57BL6JTph1tm2LexTph1tm2LexTph2tm1LexTph2tm1LexTph1tm2LexTph2tm1Lex
• abnormal serotonin level_Tph2<tm1Lex>/Tph2<tm1Lex>
  http://metadb.riken.jp/0005322I129S5SvEvBrdC57BL6JTph2tm1LexTph2tm1LexTph2tm1Lex
• abnormal response to novel object_Tph1<tm2Lex>/Tph1<tm2Lex>,Tph2<tm1Lex>/Tph2<tm1Lex>
  http://metadb.riken.jp/0003461I129S5SvEvBrdC57BL6JTph1tm2LexTph1tm2LexTph2tm1LexTph2tm1LexTph1tm2LexTph2tm1Lex
• abnormal response to novel object_Tph2<tm1Lex>/Tph2<tm1Lex>
  http://metadb.riken.jp/0003461I129S5SvEvBrdC57BL6JTph2tm1LexTph2tm1LexTph2tm1Lex
• abnormal serotonin level_Tph1<tm2Lex>/Tph1<tm2Lex>,Tph2<tm1Lex>/Tph2<tm1Lex>
  http://metadb.riken.jp/0005322I129S5SvEvBrdC57BL6JTph1tm2LexTph1tm2LexTph2tm1LexTph2tm1LexTph1tm2LexTph2tm1Lex
• abnormal serotonin level_Tph1<tm2Lex>/Tph1<tm2Lex>
  http://metadb.riken.jp/0005322I129S5SvEvBrdC57BL6JTph1tm2LexTph1tm2LexTph1tm2Lex
• decreased body weight_Tph2<tm1Lex>/Tph2<tm1Lex>
  http://metadb.riken.jp/0001262I129S5SvEvBrdC57BL6JTph2tm1LexTph2tm1LexTph2tm1Lex
• decreased body weight_Tph1<tm2Lex>/Tph1<tm2Lex>,Tph2<tm1Lex>/Tph2<tm1Lex>
  http://metadb.riken.jp/0001262I129S5SvEvBrdC57BL6JTph1tm2LexTph1tm2LexTph2tm1LexTph2tm1LexTph1tm2LexTph2tm1Lex
• abnormal emotion/affect behavior_Tph1<tm2Lex>/Tph1<tm2Lex>,Tph2<tm1Lex>/Tph2<tm1Lex>
  http://metadb.riken.jp/0002572I129S5SvEvBrdC57BL6JTph1tm2LexTph1tm2LexTph2tm1LexTph2tm1LexTph1tm2LexTph2tm1Lex
• abnormal emotion/affect behavior_Tph2<tm1Lex>/Tph2<tm1Lex>
  http://metadb.riken.jp/0002572I129S5SvEvBrdC57BL6JTph2tm1LexTph2tm1LexTph2tm1Lex

class

http://purl.org/net/cito/citesAsAuthority

• Tph2<tm1Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3831654
• Tph1<tm2Lex>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3831653