Vikas. Madan, et.al., Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog MLL5., Blood, 2009, 113

http://rdf.ncbi.nlm.nih.gov/pubmed/18952892

Vikas. Madan, et.al., Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog MLL5., Blood, 2009, 113

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3835538
• Kmt2e<tm1Hjf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3835537

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased T cell number_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0005018B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• abnormal bone marrow cell morphology/development_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0002398B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• thymus hypoplasia_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0001823B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• decreased hematopoietic stem cell number_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0004810B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• spleen hypoplasia_Kmt2e<tm1.1Hjf>/Kmt2e<+>
  http://metadb.riken.jp/0000694B6129P2Kmtetm11HjfKmt2etm11HjfKmt2eKmt2etm11HjfKmt2e
• decreased double-negative T cell number_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0005089B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• small lymph nodes_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0002217B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• decreased thymocyte number_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0000715B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• decreased thymocyte number_Kmt2e<tm1.1Hjf>/Kmt2e<+>
  http://metadb.riken.jp/0000715B6129P2Kmtetm11HjfKmt2etm11HjfKmt2eKmt2etm11HjfKmt2e
• increased mortality induced by gamma-irradiation_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0001658B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• neonatal lethality, incomplete penetrance_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0011088B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• small spleen_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0000692B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• male infertility_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0001925B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• decreased pre-B cell number_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0008209B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• postnatal lethality, incomplete penetrance_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0011086B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• reduced female fertility_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0001923B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• decreased body weight_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0001262B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• decreased common myeloid progenitor cell number_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0008813B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• decreased body size_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0001265B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• decreased hematocrit_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0000208B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• thrombocytopenia_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0003179B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• small thymus_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0000706B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• abnormal myeloblast morphology/development_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0002414B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• globozoospermia_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0002686B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• decreased B cell number_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0005017B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• decreased erythrocyte cell number_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0002875B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• decreased leukocyte cell number_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0000221B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• decreased pro-B cell number_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0008208B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• spleen hypoplasia_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0000694B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• thymus hypoplasia_Kmt2e<tm1.1Hjf>/Kmt2e<+>
  http://metadb.riken.jp/0001823B6129P2Kmtetm11HjfKmt2etm11HjfKmt2eKmt2etm11HjfKmt2e
• decreased macrophage cell number_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0003884B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• abnormal lymphopoiesis_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0002401B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf
• decreased double-positive T cell number_Kmt2e<tm1.1Hjf>/Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/0005092B6129P2Kmtetm11HjfKmt2etm11HjfKmt2etm11HjfKmt2etm11Hjf

class

http://purl.org/net/cito/citesAsAuthority

• Kmt2e<tm1.1Hjf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3835538
• Kmt2e<tm1Hjf>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3835537

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD00070
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00070