Salvatore. Cortellino, et.al., Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4., Developmental biology, 2009, 325

http://rdf.ncbi.nlm.nih.gov/pubmed/19000668

Salvatore. Cortellino, et.al., Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4., Developmental biology, 2009, 325

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• absent embryonic cilia_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0004132B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• elongated neck_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0012720B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• right-sided stomach_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0010808B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• abnormal spinal cord interneuron morphology_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0004100B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• decreased embryonic cilium length_Mbd4/Ift122<tm1Abc>/Mbd4<+>
  http://metadb.riken.jp/0011998B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Mbd4Mbd4Ift122tm1Abc
• ectrodactyly_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0005230B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• abnormal head morphology_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0000432B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• decreased embryonic cilium length_Mbd4/Ift122<tm1Abc>/Ift122<+>
  http://metadb.riken.jp/0011998B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcIft122Mbd4Ift122tm1AbcIft122
• polysyndactyly_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0004083B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• abnormal neural tube morphology_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0002151B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• abnormal abdominal wall morphology_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0003257B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• abnormal eye development_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0001286B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• abnormal cell morphology_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0000358B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• delayed limb development_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0012531B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• situs inversus_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0002766B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• embryonic lethality during organogenesis, complete penetrance_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0011098B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• enlarged heart_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0000274B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• abnormal pharyngeal arch development_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0010395B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• abnormal left-right axis patterning_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0001706B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• open neural tube_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0000929B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• exencephaly_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0000914B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• hemorrhage_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0001914B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• increased motor neuron number_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0005192B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• abnormal direction of heart looping_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0004252B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• delayed embryo turning_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0004188B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc
• abnormal limb development_Mbd4/Ift122<tm1Abc>/Mbd4/Ift122<tm1Abc>
  http://metadb.riken.jp/0006279B6129Mbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1AbcMbd4Ift122tm1Abc

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD39903
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39903
• CD32883
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD32883