Pierre-Olivier. Frappart, et.al., Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

http://rdf.ncbi.nlm.nih.gov/pubmed/19164512

Pierre-Olivier. Frappart, et.al., Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Lig4<tm1Pmc>/Lig4<tm1Pmc>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002083I129S1Sv129S2SvPasC57BL6SJLLig4tm1PmcLig4tm1PmcTrp53tm1TyjTrp53tm1TyjTgNescre1Kln0Lig4tm1PmcTrp53tm1TyjTgNescre1Kln
• increased medulloblastoma incidence_Brca2<tm1Brn>/Brca2<tm1Brn>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006283I129P2OlaHsd129S2SvPasC57BL6SJLBrca2tm1BrnBrca2tm1BrnTrp53tm1TyjTrp53tm1TyjTgNescre1Kln0Brca2tm1BrnTrp53tm1TyjTgNescre1Kln
• abnormal tumor morphology_Brca2<tm1Brn>/Brca2<tm1Brn>,Trp53<tm1Tyj>/Trp53<+>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003448I129P2OlaHsd129S2SvPasC57BL6SJLBrca2tm1BrnBrca2tm1BrnTrp53tm1TyjTrp53TgNescre1Kln0TgNescre1KlnTrp53Trp53tm1TyjBrca2tm1Brn
• increased medulloblastoma incidence_Lig4<tm1Pmc>/Lig4<tm1Pmc>,Trp53<tm1Tyj>/Trp53<+>,Xrcc2<tm2Pmc>/Xrcc2<tm2Pmc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006283I129S1Sv129S2SvPasC57BL6SJLLig4tm1PmcLig4tm1PmcTrp53tm1TyjTrp53Xrcc2tm2PmcXrcc2tm2PmcTgNescre1Kln0Xrcc2tm2PmcTgNescre1KlnTrp53Lig4tm1PmcTrp53tm1Tyj
• increased medulloblastoma incidence_Brca2<tm1Brn>/Brca2<tm1Brn>,Trp53<tm1Tyj>/Trp53<+>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006283I129P2OlaHsd129S2SvPasC57BL6SJLBrca2tm1BrnBrca2tm1BrnTrp53tm1TyjTrp53TgNescre1Kln0TgNescre1KlnTrp53Trp53tm1TyjBrca2tm1Brn
• increased medulloblastoma incidence_Brca2<tm1Brn>/Brca2<tm1Brn>,Ptch1<tm1Mps>/Ptch1<+>,Trp53<tm1Tyj>/Trp53<+>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006283I129C57BL6SJLBrca2tm1BrnBrca2tm1BrnPtch1tm1MpsPtch1Trp53tm1TyjTrp53TgNescre1Kln0Ptch1tm1MpsPtch1TgNescre1KlnTrp53Trp53tm1TyjBrca2tm1Brn
• increased medulloblastoma incidence_Brca2<tm1Brn>/Brca2<tm1Brn>,Ptch1<tm1Mps>/Ptch1<+>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006283I129C57BL6SJLBrca2tm1BrnBrca2tm1BrnPtch1tm1MpsPtch1Trp53tm1TyjTrp53tm1TyjTgNescre1Kln0Ptch1tm1MpsPtch1TgNescre1KlnTrp53tm1TyjBrca2tm1Brn
• increased medulloblastoma incidence_Lig4<tm1Pmc>/Lig4<tm1Pmc>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm2Pmc>/Xrcc2<tm2Pmc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006283I129S1Sv129S2SvPasC57BL6SJLLig4tm1PmcLig4tm1PmcTrp53tm1TyjTrp53tm1TyjXrcc2tm2PmcXrcc2tm2PmcTgNescre1Kln0TgNescre1KlnXrcc2tm2PmcTrp53tm1TyjLig4tm1Pmc
• increased medulloblastoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm2Pmc>/Xrcc2<tm2Pmc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006283I129S1Sv129S2SvPasC57BL6SJLTrp53tm1TyjTrp53tm1TyjXrcc2tm2PmcXrcc2tm2PmcTgNescre1Kln0Xrcc2tm2PmcTgNescre1KlnTrp53tm1Tyj
• abnormal tumor morphology_Lig4<tm1Pmc>/Lig4<tm1Pmc>,Trp53<tm1Tyj>/Trp53<+>,Xrcc2<tm2Pmc>/Xrcc2<tm2Pmc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003448I129S1Sv129S2SvPasC57BL6SJLLig4tm1PmcLig4tm1PmcTrp53tm1TyjTrp53Xrcc2tm2PmcXrcc2tm2PmcTgNescre1Kln0Xrcc2tm2PmcTgNescre1KlnTrp53Lig4tm1PmcTrp53tm1Tyj
• abnormal nervous system development_Lig4<tm1Pmc>/Lig4<tm1Pmc>,Meox2<tm1(cre)Sor>/Meox2<+>
  http://metadb.riken.jp/0003861I129S1Sv129S4SvJaeSorLig4tm1PmcLig4tm1PmcMeox2tm1creSorMeox2Lig4tm1PmcMeox2Meox2tm1creSor
• premature death_Lig4<tm1Pmc>/Lig4<tm1Pmc>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm2Pmc>/Xrcc2<tm2Pmc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002083I129S1Sv129S2SvPasC57BL6SJLLig4tm1PmcLig4tm1PmcTrp53tm1TyjTrp53tm1TyjXrcc2tm2PmcXrcc2tm2PmcTgNescre1Kln0TgNescre1KlnXrcc2tm2PmcTrp53tm1TyjLig4tm1Pmc
• premature death_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Xrcc2<tm2Pmc>/Xrcc2<tm2Pmc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002083I129S1Sv129S2SvPasC57BL6SJLTrp53tm1TyjTrp53tm1TyjXrcc2tm2PmcXrcc2tm2PmcTgNescre1Kln0Xrcc2tm2PmcTgNescre1KlnTrp53tm1Tyj
• increased medulloblastoma incidence_Lig4<tm1Pmc>/Lig4<tm1Pmc>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006283I129S1Sv129S2SvPasC57BL6SJLLig4tm1PmcLig4tm1PmcTrp53tm1TyjTrp53tm1TyjTgNescre1Kln0Lig4tm1PmcTrp53tm1TyjTgNescre1Kln
• premature death_Lig4<tm1Pmc>/Lig4<tm1Pmc>,Trp53<tm1Tyj>/Trp53<+>,Xrcc2<tm2Pmc>/Xrcc2<tm2Pmc>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002083I129S1Sv129S2SvPasC57BL6SJLLig4tm1PmcLig4tm1PmcTrp53tm1TyjTrp53Xrcc2tm2PmcXrcc2tm2PmcTgNescre1Kln0Xrcc2tm2PmcTgNescre1KlnTrp53Lig4tm1PmcTrp53tm1Tyj