Keisuke. Horiuchi, et.al., Conditional inactivation of TACE by a Sox9 promoter leads to osteoporosis and increased granulopoiesis via dysregulation of IL-17 and G-CSF., Journal of immunology (Baltimore, Md. : 1950), 2009, 182

http://rdf.ncbi.nlm.nih.gov/pubmed/19201862

Keisuke. Horiuchi, et.al., Conditional inactivation of TACE by a Sox9 promoter leads to osteoporosis and increased granulopoiesis via dysregulation of IL-17 and G-CSF., Journal of immunology (Baltimore, Md. : 1950), 2009, 182

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal hair growth_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0002073I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• decreased bone mass_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0004016I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• increased spleen red pulp amount_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0008476I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• osteoporosis_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0000066I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• short femur_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0003109I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• early eyelid opening_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0003153I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• decreased length of long bones_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0004686I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• abnormal skin condition_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0001191I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• decreased trabecular bone thickness_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0009346I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• increased neutrophil cell number_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0000219I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• increased circulating interleukin-17 level_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0008614I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• premature death_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• reduced male fertility_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0001922I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• extramedullary hematopoiesis_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0000240I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• enlarged spleen_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0000691I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• decreased hematocrit_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0000208I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• increased interleukin-17 secretion_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0008681I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• abnormal spleen morphology_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0000689I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• increased bone marrow cell number_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0000321I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• decreased compact bone thickness_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0000135I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• abnormal bone remodeling_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0002998I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• female infertility_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0001926I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• decreased body weight_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0001262I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• increased hemoglobin content_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0005564I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• abnormal bone marrow cavity morphology_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0000065I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• increased leukocyte cell number_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0000218I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• decreased B cell number_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0005017I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• thrombocytosis_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0005505I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• decreased T cell number_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0005018I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• decreased lymphocyte cell number_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0005016I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• postnatal growth retardation_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0001732I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• abnormal long bone epiphyseal plate proliferative zone_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0003662I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• increased macrophage cell number_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0005425I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl
• abnormal long bone hypertrophic chondrocyte zone_Adam17<tm1.2Bbl>/Adam17<tm1.2Bbl>,Sox9<tm3(cre)Crm>/Sox9<+>
  http://metadb.riken.jp/0000165I129P2OlaHsd129S7SvEvBrdC57BL6Adam17tm12BblAdam17tm12BblSox9tm3creCrmSox9Sox9Sox9tm3creCrmAdam17tm12Bbl