Hisanobu. Oda, et.al., Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development., Molecular and cellular biology, 2009, 29

http://rdf.ncbi.nlm.nih.gov/pubmed/19223465

Hisanobu. Oda, et.al., Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development., Molecular and cellular biology, 2009, 29

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Kmt5a<tm1.1Dare>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3842472
• Kmt5a<tm1.2Dare>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3842473

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal DNA replication_Kmt5a<tm1.1Dare>/Kmt5a<tm1.2Dare>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008057I129S1SvC57BL6CBASJLKmt5atm11DareKmt5atm12DareTgCAGcreEsr15Amc0TgCAGcreEsr15AmcKmt5atm12DareKmt5atm11Dare
• embryonic lethality before implantation, complete penetrance_Kmt5a<tm1.2Dare>/Kmt5a<tm1.2Dare>
  http://metadb.riken.jp/0011094I129S1SvC57BL6CBASJLKmt5atm12DareKmt5atm12DareKmt5atm12Dare
• failure of zygotic cell division_Kmt5a<tm1.2Dare>/Kmt5a<tm1.2Dare>
  http://metadb.riken.jp/0003406I129S1SvC57BL6CBASJLKmt5atm12DareKmt5atm12DareKmt5atm12Dare
• abnormal cell cycle checkpoint function_Kmt5a<tm1.1Dare>/Kmt5a<tm1.2Dare>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0004045I129S1SvC57BL6CBASJLKmt5atm11DareKmt5atm12DareTgCAGcreEsr15Amc0TgCAGcreEsr15AmcKmt5atm12DareKmt5atm11Dare
• increased apoptosis_Kmt5a<tm1.1Dare>/Kmt5a<tm1.2Dare>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0006042I129S1SvC57BL6CBASJLKmt5atm11DareKmt5atm12DareTgCAGcreEsr15Amc0TgCAGcreEsr15AmcKmt5atm12DareKmt5atm11Dare
• abnormal cell physiology_Kmt5a<tm1.1Dare>/Kmt5a<tm1.2Dare>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0005621I129S1SvC57BL6CBASJLKmt5atm11DareKmt5atm12DareTgCAGcreEsr15Amc0TgCAGcreEsr15AmcKmt5atm12DareKmt5atm11Dare
• no abnormal phenotype detected_Kmt5a<tm1.1Dare>/Kmt5a<tm1.1Dare>
  http://metadb.riken.jp/0002169I129S1SvC57BL6SJLKmt5atm11DareKmt5atm11DareKmt5atm11Dare
• abnormal DNA repair_Kmt5a<tm1.1Dare>/Kmt5a<tm1.2Dare>,Tg(CAG-cre/Esr1*)5Amc/0
  http://metadb.riken.jp/0008058I129S1SvC57BL6CBASJLKmt5atm11DareKmt5atm12DareTgCAGcreEsr15Amc0TgCAGcreEsr15AmcKmt5atm12DareKmt5atm11Dare

class

http://purl.org/net/cito/citesAsAuthority

• Kmt5a<tm1.1Dare>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3842472
• Kmt5a<tm1.2Dare>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3842473

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD09601
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD09601
• CD07187
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD07187