Steven J. Clapcote, et.al., Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

http://rdf.ncbi.nlm.nih.gov/pubmed/19666602

Steven J. Clapcote, et.al., Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Atp1a3<Myk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4356167
• Tg(Atp1a3)1Stcl
  http://metadb.riken.jp/db/mgi_rdf/MGI:4356322

class

http://purl.org/net/cito/citesAsAuthority

• Atp1a3<Myk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4356167
• Tg(Atp1a3)1Stcl
  http://metadb.riken.jp/db/mgi_rdf/MGI:4356322

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased body size_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0001265I129S1SvImJC57BL6JC57BL6NCrAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• astrocytosis_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0003354I129S1SvImJC57BL6JC57BL6NCrFVBNCrAtp1a3MykAtp1a3Atp1a3MykAtp1a3
• abnormal temporal lobe morphology_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0000801B6NCr129S1Atp1a3MykAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• premature death_Atp1a3<Myk>/Atp1a3<tm1Ling>
  http://metadb.riken.jp/0002083I129S1SvImJC57BL6JC57BL6NCrAtp1a3MykAtp1a3tm1LingAtp1a3MykAtp1a3tm1Ling
• microgliosis_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0008918I129S1SvImJC57BL6JC57BL6NCrFVBNCrAtp1a3MykAtp1a3Atp1a3MykAtp1a3
• abnormal hippocampus pyramidal cell morphology_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0009940B6NCr129S1Atp1a3MykAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• decreased body size_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0001265B6NCr129S1Atp1a3MykAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• premature death_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0002083I129S1SvImJC57BL6JC57BL6NCrAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• neonatal lethality, complete penetrance_Atp1a3<Myk>/Atp1a3<Myk>
  http://metadb.riken.jp/0011087I129S1SvImJC57BL6JC57BL6NCrAtp1a3MykAtp1a3MykAtp1a3Myk
• abnormal hippocampus pyramidal cell morphology_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0009940I129S1SvImJC57BL6JC57BL6NCrAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• abnormal temporal lobe morphology_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0000801I129S1SvImJC57BL6JC57BL6NCrAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• abnormal spike wave discharge_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0008840I129S1SvImJC57BL6JC57BL6NCrAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• environmentally induced seizures_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0009358B6NCr129S1Atp1a3MykAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• convulsive seizures_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0000947B6NCr129S1Atp1a3MykAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• premature death_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0002083B6NCr129S1Atp1a3MykAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• decreased body weight_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0001262B6NCr129S1Atp1a3MykAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• environmentally induced seizures_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0009358I129S1SvImJC57BL6JC57BL6NCrAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• convulsive seizures_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0000947I129S1SvImJC57BL6JC57BL6NCrAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• abnormal spike wave discharge_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0008840B6NCr129S1Atp1a3MykAtp1a3MykAtp1a3Atp1a3Atp1a3Myk
• decreased body weight_Atp1a3<Myk>/Atp1a3<+>
  http://metadb.riken.jp/0001262I129S1SvImJC57BL6JC57BL6NCrAtp1a3MykAtp1a3Atp1a3Atp1a3Myk

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD07628
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD07628