Kyle D. Copps, et.al., Irs1 serine 307 promotes insulin sensitivity in mice., Cell metabolism, 2010, 11

http://rdf.ncbi.nlm.nih.gov/pubmed/20074531

Kyle D. Copps, et.al., Irs1 serine 307 promotes insulin sensitivity in mice., Cell metabolism, 2010, 11

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Irs1<tm2.1Mfw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4430350
• Irs1<tm3.1Mfw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4430351

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired glucose tolerance_Irs1<tm2.1Mfw>/Irs1<tm2.1Mfw>,Irs2<tm2Mfw>/Irs2<tm2Mfw>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005293I129S1Sv129X1SvJC57BL6JDBAFVBNIrs1tm21MfwIrs1tm21MfwIrs2tm2MfwIrs2tm2MfwTgAlbcre21Mgn0Irs2tm2MfwIrs1tm21MfwTgAlbcre21Mgn
• increased circulating insulin level_Irs1<tm2.1Mfw>/Irs1<tm2.1Mfw>
  http://metadb.riken.jp/0002079I129S1Sv129X1SvJC57BL6JFVBNIrs1tm21MfwIrs1tm21MfwIrs1tm21Mfw
• impaired glucose tolerance_Irs1<tm1Mfw>/Irs1<tm2.1Mfw>,Irs2<tm2Mfw>/Irs2<tm2Mfw>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005293I129S1Sv129X1SvJC57BL6JDBAFVBNIrs1tm1MfwIrs1tm21MfwIrs2tm2MfwIrs2tm2MfwTgAlbcre21Mgn0Irs1tm1MfwIrs2tm2MfwTgAlbcre21MgnIrs1tm21Mfw
• impaired glucose tolerance_Irs1<tm2.1Mfw>/Irs1<tm2.1Mfw>
  http://metadb.riken.jp/0005293I129S1Sv129X1SvJC57BL6JFVBNIrs1tm21MfwIrs1tm21MfwIrs1tm21Mfw
• decreased body weight_Irs1<tm3.1Mfw>/Irs1<tm3.1Mfw>
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJC57BL6JFVBNIrs1tm31MfwIrs1tm31MfwIrs1tm31Mfw
• insulin resistance_Irs1<tm1Mfw>/Irs1<tm2.1Mfw>,Irs2<tm2Mfw>/Irs2<tm2Mfw>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005331I129S1Sv129X1SvJC57BL6JDBAFVBNIrs1tm1MfwIrs1tm21MfwIrs2tm2MfwIrs2tm2MfwTgAlbcre21Mgn0Irs1tm1MfwIrs2tm2MfwTgAlbcre21MgnIrs1tm21Mfw
• increased circulating insulin level_Irs1<tm2.1Mfw>/Irs1<tm2.1Mfw>,Irs2<tm2Mfw>/Irs2<tm2Mfw>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002079I129S1Sv129X1SvJC57BL6JDBAFVBNIrs1tm21MfwIrs1tm21MfwIrs2tm2MfwIrs2tm2MfwTgAlbcre21Mgn0Irs2tm2MfwIrs1tm21MfwTgAlbcre21Mgn
• increased circulating insulin level_Irs1<tm2.1Mfw>/Irs1<+>
  http://metadb.riken.jp/0002079I129S1Sv129X1SvJC57BL6JFVBNIrs1tm21MfwIrs1Irs1Irs1tm21Mfw
• increased circulating insulin level_Irs1<tm1Mfw>/Irs1<tm2.1Mfw>,Irs2<tm2Mfw>/Irs2<tm2Mfw>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0002079I129S1Sv129X1SvJC57BL6JDBAFVBNIrs1tm1MfwIrs1tm21MfwIrs2tm2MfwIrs2tm2MfwTgAlbcre21Mgn0Irs1tm1MfwIrs2tm2MfwTgAlbcre21MgnIrs1tm21Mfw
• decreased body length_Irs1<tm3.1Mfw>/Irs1<tm3.1Mfw>
  http://metadb.riken.jp/0001258I129S1Sv129X1SvJC57BL6JFVBNIrs1tm31MfwIrs1tm31MfwIrs1tm31Mfw
• impaired glucose tolerance_Irs1<tm1Mfw>/Irs1<+>,Irs2<tm2Mfw>/Irs2<tm2Mfw>,Tg(Alb-cre)21Mgn/0
  http://metadb.riken.jp/0005293I129S1Sv129X1SvJC57BL6JDBAFVBNIrs1tm1MfwIrs1Irs2tm2MfwIrs2tm2MfwTgAlbcre21Mgn0Irs2tm2MfwIrs1Irs1tm1MfwTgAlbcre21Mgn
• decreased bone mineral density_Irs1<tm3.1Mfw>/Irs1<tm3.1Mfw>
  http://metadb.riken.jp/0000063I129S1Sv129X1SvJC57BL6JFVBNIrs1tm31MfwIrs1tm31MfwIrs1tm31Mfw
• decreased body length_Irs1<tm2.1Mfw>/Irs1<tm2.1Mfw>
  http://metadb.riken.jp/0001258I129S1Sv129X1SvJC57BL6JFVBNIrs1tm21MfwIrs1tm21MfwIrs1tm21Mfw
• abnormal pancreatic beta cell morphology_Irs1<tm2.1Mfw>/Irs1<+>
  http://metadb.riken.jp/0005217I129S1Sv129X1SvJC57BL6JFVBNIrs1tm21MfwIrs1Irs1Irs1tm21Mfw
• abnormal pancreatic beta cell morphology_Irs1<tm2.1Mfw>/Irs1<tm2.1Mfw>
  http://metadb.riken.jp/0005217I129S1Sv129X1SvJC57BL6JFVBNIrs1tm21MfwIrs1tm21MfwIrs1tm21Mfw
• decreased body weight_Irs1<tm2.1Mfw>/Irs1<tm2.1Mfw>
  http://metadb.riken.jp/0001262I129S1Sv129X1SvJC57BL6JFVBNIrs1tm21MfwIrs1tm21MfwIrs1tm21Mfw
• insulin resistance_Irs1<tm2.1Mfw>/Irs1<tm2.1Mfw>
  http://metadb.riken.jp/0005331I129S1Sv129X1SvJC57BL6JFVBNIrs1tm21MfwIrs1tm21MfwIrs1tm21Mfw

class

http://purl.org/net/cito/citesAsAuthority

• Irs1<tm2.1Mfw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4430350
• Irs1<tm3.1Mfw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4430351