Sonja J. Heidorn, et.al., Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF., Cell, 2010, 140

http://rdf.ncbi.nlm.nih.gov/pubmed/20141835

Sonja J. Heidorn, et.al., Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF., Cell, 2010, 140

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Braf<tm1Rima>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4458346

class

http://purl.org/net/cito/citesAsAuthority

• Braf<tm1Rima>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4458346

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hyperpigmentation_Braf<tm1Rima>/Braf<+>,Kras<tm4Tyj>/Kras<+>,Tg(Tyr-cre/ERT2)1Lru/0
  http://metadb.riken.jp/0001188I129S4SvJaeC57BL6DBA2Braftm1RimaBrafKrastm4TyjKrasTgTyrcreERT21Lru0KrasKrastm4TyjBrafBraftm1RimaTgTyrcreERT21Lru
• increased tumor incidence_Braf<tm1Rima>/Braf<+>,Kras<tm4Tyj>/Kras<+>,Tg(Tyr-cre/ERT2)1Lru/0
  http://metadb.riken.jp/0002020I129S4SvJaeC57BL6DBA2Braftm1RimaBrafKrastm4TyjKrasTgTyrcreERT21Lru0KrasKrastm4TyjBrafBraftm1RimaTgTyrcreERT21Lru
• increased melanoma incidence_Braf<tm1Rima>/Braf<+>,Tg(GFP/KRAS2/ALPP)1Brn/0,Tg(Tyr-cre/ERT2)1Lru/0
  http://metadb.riken.jp/0010275IC57BL6DBA2FVBNBraftm1RimaBrafTgGFPKRAS2ALPP1Brn0TgTyrcreERT21Lru0BrafTgTyrcreERT21LruBraftm1RimaTgGFPKRAS2ALPP1Brn