Jonathan L. Brigman, et.al., Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30

http://rdf.ncbi.nlm.nih.gov/pubmed/20357110

Jonathan L. Brigman, et.al., Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Grin2b<tm1.1Jlbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4443321

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased physiological sensitivity to xenobiotic_Grin2b<tm1.1Jlbr>/Grin2b<tm1.1Jlbr>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0008874I129S6SvEvTacBALBcC57BL6Grin2btm11JlbrGrin2btm11JlbrTgCamk2acreT291Stl0TgCamk2acreT291StlGrin2btm11Jlbr
• absent long term depression_Grin2b<tm1.1Jlbr>/Grin2b<tm1.1Jlbr>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001899I129S6SvEvTacBALBcC57BL6Grin2btm11JlbrGrin2btm11JlbrTgCamk2acreT291Stl0TgCamk2acreT291StlGrin2btm11Jlbr
• abnormal learning/memory/conditioning_Grin2b<tm1.1Jlbr>/Grin2b<tm1.1Jlbr>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0002063I129S6SvEvTacBALBcC57BL6Grin2btm11JlbrGrin2btm11JlbrTgCamk2acreT291Stl0TgCamk2acreT291StlGrin2btm11Jlbr
• abnormal dendritic spine morphology_Grin2b<tm1.1Jlbr>/Grin2b<tm1.1Jlbr>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0009936I129S6SvEvTacBALBcC57BL6Grin2btm11JlbrGrin2btm11JlbrTgCamk2acreT291Stl0TgCamk2acreT291StlGrin2btm11Jlbr
• abnormal associative learning_Grin2b<tm1.1Jlbr>/Grin2b<tm1.1Jlbr>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0002062I129S6SvEvTacBALBcC57BL6Grin2btm11JlbrGrin2btm11JlbrTgCamk2acreT291Stl0TgCamk2acreT291StlGrin2btm11Jlbr
• abnormal excitatory postsynaptic currents_Grin2b<tm1.1Jlbr>/Grin2b<tm1.1Jlbr>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0002910I129S6SvEvTacBALBcC57BL6Grin2btm11JlbrGrin2btm11JlbrTgCamk2acreT291Stl0TgCamk2acreT291StlGrin2btm11Jlbr
• increased thigmotaxis_Grin2b<tm1.1Jlbr>/Grin2b<tm1.1Jlbr>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0002797I129S6SvEvTacBALBcC57BL6Grin2btm11JlbrGrin2btm11JlbrTgCamk2acreT291Stl0TgCamk2acreT291StlGrin2btm11Jlbr
• impaired swimming_Grin2b<tm1.1Jlbr>/Grin2b<tm1.1Jlbr>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001522I129S6SvEvTacBALBcC57BL6Grin2btm11JlbrGrin2btm11JlbrTgCamk2acreT291Stl0TgCamk2acreT291StlGrin2btm11Jlbr
• abnormal spatial learning_Grin2b<tm1.1Jlbr>/Grin2b<tm1.1Jlbr>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001463I129S6SvEvTacBALBcC57BL6Grin2btm11JlbrGrin2btm11JlbrTgCamk2acreT291Stl0TgCamk2acreT291StlGrin2btm11Jlbr
• abnormal excitatory postsynaptic potential_Grin2b<tm1.1Jlbr>/Grin2b<tm1.1Jlbr>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0002912I129S6SvEvTacBALBcC57BL6Grin2btm11JlbrGrin2btm11JlbrTgCamk2acreT291Stl0TgCamk2acreT291StlGrin2btm11Jlbr
• reduced long term depression_Grin2b<tm1.1Jlbr>/Grin2b<tm1.1Jlbr>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001475I129S6SvEvTacBALBcC57BL6Grin2btm11JlbrGrin2btm11JlbrTgCamk2acreT291Stl0TgCamk2acreT291StlGrin2btm11Jlbr
• reduced long term potentiation_Grin2b<tm1.1Jlbr>/Grin2b<tm1.1Jlbr>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001473I129S6SvEvTacBALBcC57BL6Grin2btm11JlbrGrin2btm11JlbrTgCamk2acreT291Stl0TgCamk2acreT291StlGrin2btm11Jlbr

class

http://purl.org/net/cito/citesAsAuthority

• Grin2b<tm1.1Jlbr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4443321