Xiang. Zhou, et.al., Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/20439739

Xiang. Zhou, et.al., Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pik3c3<tm1Fawa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459941
• Avil<tm2(cre)Fawa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459942

class

http://purl.org/net/cito/citesAsAuthority

• Pik3c3<tm1Fawa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459941
• Avil<tm2(cre)Fawa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459942

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• tremors_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0000745IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• hindlimb paralysis_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0000755NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• abnormal sensory neuron morphology_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0000965IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• abnormal sensory neuron morphology_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0000965NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• decreased sensory neuron number_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0000966NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• impaired coordination_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0001405NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
他13件を見る
• abnormal posture_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0001504NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• limb grasping_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0001513IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• no abnormal phenotype detected_Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0002169NSPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1Fawa
• gliosis_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0002183IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• neurodegeneration_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0002229IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• neurodegeneration_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0002229NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• curly tail_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0003051IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• increased neuron apoptosis_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0003203IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• increased neuron apoptosis_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0003203NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• abnormal proprioceptive neuron morphology_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0004297NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• bradykinesia_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0005156IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• axon degeneration_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0005405NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• postnatal lethality, complete penetrance_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0011085NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD16951
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16951
• CD21388
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD21388

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

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article

http://www.w3.org/2000/01/rdf-schema#seeAlso

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