Xiang. Zhou, et.al., Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/20439739

Xiang. Zhou, et.al., Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

rdfs:label

http://www.w3.org/2000/01/rdf-schema#label

• Xiang. Zhou, et.al., Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]

class

http://purl.org/net/cito/citesAsAuthority

• Pik3c3<tm1Fawa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459941
• Avil<tm2(cre)Fawa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459942

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal proprioceptive neuron morphology_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0004297NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• neurodegeneration_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0002229NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• postnatal lethality, complete penetrance_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0011085NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• hindlimb paralysis_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0000755NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• gliosis_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0002183IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• tremors_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0000745IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• increased neuron apoptosis_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0003203NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• decreased sensory neuron number_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0000966NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• abnormal sensory neuron morphology_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0000965IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• curly tail_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0003051IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• abnormal sensory neuron morphology_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0000965NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• axon degeneration_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0005405NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• neurodegeneration_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0002229IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• bradykinesia_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0005156IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• impaired coordination_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0001405NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• increased neuron apoptosis_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0003203IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil
• abnormal posture_Avil<tm2(cre)Fawa>/Avil<+>,Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0001504NSAviltm2creFawaAvilPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1FawaAvilAviltm2creFawa
• no abnormal phenotype detected_Pik3c3<tm1Fawa>/Pik3c3<tm1Fawa>
  http://metadb.riken.jp/0002169NSPik3c3tm1FawaPik3c3tm1FawaPik3c3tm1Fawa
• limb grasping_Atg7<tm1Tchi>/Atg7<tm1Tchi>,Avil<tm2(cre)Fawa>/Avil<+>
  http://metadb.riken.jp/0001513IC57BL6CBAAtg7tm1TchiAtg7tm1TchiAviltm2creFawaAvilAviltm2creFawaAtg7tm1TchiAvil

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD21388
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD21388
• CD16951
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16951

allele

http://purl.org/net/cito/citesAsAuthority

• Pik3c3<tm1Fawa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459941
• Avil<tm2(cre)Fawa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4459942