Ya-Jing. Peng, et.al., Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum., The Journal of biological chemistry, 2010, 285

http://rdf.ncbi.nlm.nih.gov/pubmed/20516067

Ya-Jing. Peng, et.al., Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum., The Journal of biological chemistry, 2010, 285

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(GFAP-cre)#Mzhu
  http://metadb.riken.jp/db/mgi_rdf/MGI:4839234
• Trio<tm1Mzhu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4839231

class

http://purl.org/net/cito/citesAsAuthority

• Tg(GFAP-cre)#Mzhu
  http://metadb.riken.jp/db/mgi_rdf/MGI:4839234
• Trio<tm1Mzhu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4839231

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal cerebellar granule layer morphology_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0000886I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• small olfactory bulb_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0002741I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• abnormal cerebellum lobule morphology_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0009964I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• abnormal Bergmann glial cell morphology_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0010387I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• small cerebellum_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0000852I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• absent gastric milk in neonates_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0009546I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• decreased brain size_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0000774I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• decreased body weight_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0001262I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• abnormal dentate gyrus morphology_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0000812I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• abnormal rostral migratory stream morphology_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0004279I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• postnatal growth retardation_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0001732I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• abnormal cerebellum external granule cell layer morphology_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0000872I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• abnormal olfactory bulb mitral cell layer morphology_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0009951I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• postnatal lethality, complete penetrance_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0011085I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• abnormal neuron differentiation_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0009937I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• increased neuron apoptosis_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0003203I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• abnormal cerebellar granule cell morphology_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0004098I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• abnormal cerebellar granule cell migration_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0009977I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• neonatal lethality, incomplete penetrance_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0011088I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• ataxia_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0001393I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln
• limb grasping_Tg(Nes-cre)1Kln/0,Trio<tm1Mzhu>/Trio<tm1Mzhu>
  http://metadb.riken.jp/0001513I129S6SvEvTacC57BL6SJLTgNescre1Kln0Triotm1MzhuTriotm1MzhuTriotm1MzhuTgNescre1Kln

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD01054
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01054