Albert. Quintana, et.al., Complex I deficiency due to loss of Ndufs4 in the brain results in progressive encephalopathy resembling Leigh syndrome., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/20534480

Albert. Quintana, et.al., Complex I deficiency due to loss of Ndufs4 in the brain results in progressive encephalopathy resembling Leigh syndrome., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• limb grasping_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001513I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• cataract_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001304I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• hypoactivity_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(UBC-cre/ERT2)1Ejb/0
  http://metadb.riken.jp/0001402I129SSvEv129S4SvJaeSorC57BL6GtROSA26Sortm1SorGtROSA26SorNdufs4tm1RpaNdufs4tm1RpaTgUBCcreERT21Ejb0TgUBCcreERT21EjbGtROSA26SorGtROSA26Sortm1SorNdufs4tm1Rpa
• abnormal nest building behavior_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001447I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• decreased body size_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001265I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• gliosis_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0002183I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal breathing pattern_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001951I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• impaired coordination_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001405I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• decreased body length_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001258I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• abnormal sensory capabilities/reflexes/nociception_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002067I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• decreased startle reflex_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001489I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• Purkinje cell degeneration_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0000876I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal brain vasculature morphology_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0004950I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• decreased grooming behavior_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001442I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• postnatal growth retardation_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001732I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• impaired coordination_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(UBC-cre/ERT2)1Ejb/0
  http://metadb.riken.jp/0001405I129SSvEv129S4SvJaeSorC57BL6GtROSA26Sortm1SorGtROSA26SorNdufs4tm1RpaNdufs4tm1RpaTgUBCcreERT21Ejb0TgUBCcreERT21EjbGtROSA26SorGtROSA26Sortm1SorNdufs4tm1Rpa
• lethargy_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005202I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• respiratory distress_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(UBC-cre/ERT2)1Ejb/0
  http://metadb.riken.jp/0001954I129SSvEv129S4SvJaeSorC57BL6GtROSA26Sortm1SorGtROSA26SorNdufs4tm1RpaNdufs4tm1RpaTgUBCcreERT21Ejb0TgUBCcreERT21EjbGtROSA26SorGtROSA26Sortm1SorNdufs4tm1Rpa
• hypoactivity_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001402I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• decreased heart rate_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0005333I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• lethargy_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0005202I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal neuron physiology_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0004811I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• spongiform encephalopathy_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0002654I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• blepharoptosis_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001344I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• cataract_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001304I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• axonal spheroids_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0010047I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal nest building behavior_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001447I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• intracranial hemorrhage_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001915I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• positive geotaxis_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0005356I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• respiratory distress_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001954I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• decreased aggression_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005656I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• abnormal body weight_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001259I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• hypoactivity_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001402I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• circling_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001394I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• decreased vocalization_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0020351I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• microgliosis_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0008918I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• hyperekplexia_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0005604I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal emotion/affect behavior_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0002572I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal motor coordination/ balance_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001516I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• microgliosis_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008918I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• impaired balance_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001525I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal vision_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0002090I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal posture_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001504I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• trunk curl_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001512I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• ataxia_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001393I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• kyphosis_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000160I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• abnormal gait_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001406I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• astrocytosis_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0003354I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• ataxia_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001393I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• kyphosis_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0000160I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• optic nerve atrophy_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001059I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• tremors_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000745I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• weight loss_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001263I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• decreased body temperature_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005534I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• hyporesponsive to tactile stimuli_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0005498I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• hyporesponsive to tactile stimuli_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005498I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• decreased grooming behavior_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001442I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• optic nerve atrophy_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001059I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• impaired righting response_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001523I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• environmentally induced seizures_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009358I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• decreased heart rate_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005333I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• gliosis_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002183I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• brainstem hemorrhage_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006051I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• trunk curl_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001512I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• abnormal emotion/affect behavior_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002572I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• hyperekplexia_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0005604I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• tonic-clonic seizures_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003997I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• impaired swimming_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001522I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• decreased startle reflex_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001489I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal brain vasculature morphology_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004950I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• limb grasping_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001513I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal muscle tone_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0004142I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• retropulsion_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0010323I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• limb grasping_Gt(ROSA)26Sor<tm1Sor>/Gt(ROSA)26Sor<+>,Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(UBC-cre/ERT2)1Ejb/0
  http://metadb.riken.jp/0001513I129SSvEv129S4SvJaeSorC57BL6GtROSA26Sortm1SorGtROSA26SorNdufs4tm1RpaNdufs4tm1RpaTgUBCcreERT21Ejb0TgUBCcreERT21EjbGtROSA26SorGtROSA26Sortm1SorNdufs4tm1Rpa
• tremors_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0000745I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• brain vacuoles_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0008025I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• impaired righting response_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001523I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal vision_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002090I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• decreased aggression_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0005656I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• seizures_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0002064I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• circling_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001394I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal gait_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001406I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• impaired balance_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001525I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• premature death_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002083I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• abnormal posture_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001504I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• impaired coordination_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001405I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• decreased body temperature_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0005534I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• decreased vocalization_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0020351I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• abnormal sensory capabilities/reflexes/nociception_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0002067I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• respiratory distress_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001954I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• straub tail_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0003382I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• impaired swimming_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001522I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal breathing pattern_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001951I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• decreased body length_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001258I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal respiratory electron transport chain_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0010955I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• abnormal muscle tone_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0004142I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• environmentally induced seizures_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0009358I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• oxidative stress_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0003674I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• neuron degeneration_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0003224I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• brainstem hemorrhage_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0006051I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• abnormal mitochondrial crista morphology_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0011635I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• blepharoptosis_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001344I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• decreased body size_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001265I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• postnatal growth retardation_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001732I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa
• straub tail_Ndufs4<tm1Rpa>/Ndufs4<tm1Rpa>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0003382I129S4SvJaeSorC57BL6SJLNdufs4tm1RpaNdufs4tm1RpaTgNescre1Kln0TgNescre1KlnNdufs4tm1Rpa
• abnormal motor coordination/ balance_Ndufs4<tm1.1Rpa>/Ndufs4<tm1.1Rpa>
  http://metadb.riken.jp/0001516I129S4SvJaeSorNdufs4tm11RpaNdufs4tm11RpaNdufs4tm11Rpa

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD00894
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00894