Roberta. Sottocornola, et.al., ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development., Developmental cell, 2010, 19

http://rdf.ncbi.nlm.nih.gov/pubmed/20619750

Roberta. Sottocornola, et.al., ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development., Developmental cell, 2010, 19

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Trp53bp2<tm2Xlu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4819167

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hydroencephaly_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0001891C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal stratification in cerebral cortex_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0000790C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal embryonic neuroepithelium morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0004261C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal retinal progenitor cell morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0006071I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal retina morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0001325I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• increased neuron apoptosis_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0003203I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal choroid plexus morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0000820C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• dilated brain ventricles_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0012676I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal embryonic neuroepithelial cell proliferation_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0012704I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal kidney physiology_Gt(ROSA)26Sor<tm1(cre/ERT)Brn>/Gt(ROSA)26Sor<+>,Trp53bp2<tm2Xlu>/Trp53bp2<tm2Xlu>
  http://metadb.riken.jp/0002136I129P2OlaHsdGtROSA26Sortm1creERTBrnGtROSA26SorTrp53bp2tm2XluTrp53bp2tm2XluTrp53bp2tm2XluGtROSA26SorGtROSA26Sortm1creERTBrn
• abnormal retina morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0001325C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• postnatal lethality, complete penetrance_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0011085I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal embryonic neuroepithelial cell proliferation_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0012704C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• decreased body size_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0001265I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal embryonic/fetal subventricular zone morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0004274I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal cortical plate morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0008439C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal brain morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0002152I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal neuronal migration_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0006009C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal neuron differentiation_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0009937C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal cerebral cortex morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0000788C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• perinatal lethality, incomplete penetrance_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0011090I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal brain morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0002152C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• hydroencephaly_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0001891I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal retinal photoreceptor layer morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0003728I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal neuronal precursor proliferation_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0004948I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal retinal outer nuclear layer morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0003731I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• disorganized retinal layers_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0001328C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• increased neuronal precursor cell number_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0004980I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal cortical ventricular zone morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0008458I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal cortical ventricular zone morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0008458C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• increased embryonic neuroepithelial cell proliferation_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0012705I129S6SvEvTacC57BL6JTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu
• abnormal embryonic/fetal subventricular zone morphology_Trp53bp2<tm1Xlu>/Trp53bp2<tm1Xlu>
  http://metadb.riken.jp/0004274C129S6Trp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1XluTrp53bp2tm1Xlu

class

http://purl.org/net/cito/citesAsAuthority

• Trp53bp2<tm2Xlu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4819167

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD04686
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04686
• CD03247
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03247
• CD27768
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD27768