Junya. Kuroda, et.al., NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

http://rdf.ncbi.nlm.nih.gov/pubmed/20713697

Junya. Kuroda, et.al., NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nox4<tm1.1Jusa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4830885

class

http://purl.org/net/cito/citesAsAuthority

• Nox4<tm1.1Jusa>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4830885

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased sensitivity to induced morbidity/mortality_Nox4<tm1.1Jusa>/Nox4<tm1.1Jusa>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0009764IC57BL6FVBNox4tm11JusaNox4tm11JusaTgMyh6cre2182Mds0TgMyh6cre2182MdsNox4tm11Jusa
• cardiac interstitial fibrosis_Nox4<tm1.1Jusa>/Nox4<tm1.1Jusa>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0005608IC57BL6FVBNox4tm11JusaNox4tm11JusaTgMyh6cre2182Mds0TgMyh6cre2182MdsNox4tm11Jusa
• oxidative stress_Nox4<tm1.1Jusa>/Nox4<tm1.1Jusa>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0003674IC57BL6FVBNox4tm11JusaNox4tm11JusaTgMyh6cre2182Mds0TgMyh6cre2182MdsNox4tm11Jusa
• cardiac hypertrophy_Tg(Myh6-Nox4)13Jusa/0
  http://metadb.riken.jp/0001625FVBTgMyh6Nox413JusaTgMyh6Nox413Jusa0TgMyh6Nox413Jusa
• abnormal mitochondrial physiology_Nox4<tm1.1Jusa>/Nox4<tm1.1Jusa>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0006036IC57BL6FVBNox4tm11JusaNox4tm11JusaTgMyh6cre2182Mds0TgMyh6cre2182MdsNox4tm11Jusa
• abnormal mitochondrial physiology_Tg(Myh6-Nox4)#Jusa/0
  http://metadb.riken.jp/0006036FVBTgMyh6Nox4JusaTgMyh6Nox4Jusa0TgMyh6Nox4Jusa
• abnormal ventricle myocardium morphology_Tg(Myh6-Nox4)#Jusa/0
  http://metadb.riken.jp/0010499FVBTgMyh6Nox4JusaTgMyh6Nox4Jusa0TgMyh6Nox4Jusa
• cardiac hypertrophy_Tg(Myh6-Nox4)3Jusa/0
  http://metadb.riken.jp/0001625FVBTgMyh6Nox43JusaTgMyh6Nox43Jusa0TgMyh6Nox43Jusa
• decreased ventricle muscle contractility_Tg(Myh6-Nox4)#Jusa/0
  http://metadb.riken.jp/0005598FVBTgMyh6Nox4JusaTgMyh6Nox4Jusa0TgMyh6Nox4Jusa
• cardiac fibrosis_Tg(Myh6-Nox4)#Jusa/0
  http://metadb.riken.jp/0003141FVBTgMyh6Nox4JusaTgMyh6Nox4Jusa0TgMyh6Nox4Jusa
• heart left ventricle hypertrophy_Nox4<tm1.1Jusa>/Nox4<tm1.1Jusa>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0002625IC57BL6FVBNox4tm11JusaNox4tm11JusaTgMyh6cre2182Mds0TgMyh6cre2182MdsNox4tm11Jusa
• decreased cardiomyocyte apoptosis_Nox4<tm1.1Jusa>/Nox4<tm1.1Jusa>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0003223IC57BL6FVBNox4tm11JusaNox4tm11JusaTgMyh6cre2182Mds0TgMyh6cre2182MdsNox4tm11Jusa
• oxidative stress_Tg(Myh6-Nox4)#Jusa/0
  http://metadb.riken.jp/0003674FVBTgMyh6Nox4JusaTgMyh6Nox4Jusa0TgMyh6Nox4Jusa
• decreased ventricle muscle contractility_Nox4<tm1.1Jusa>/Nox4<tm1.1Jusa>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0005598IC57BL6FVBNox4tm11JusaNox4tm11JusaTgMyh6cre2182Mds0TgMyh6cre2182MdsNox4tm11Jusa
• decreased cardiac muscle contractility_Nox4<tm1.1Jusa>/Nox4<tm1.1Jusa>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0005140IC57BL6FVBNox4tm11JusaNox4tm11JusaTgMyh6cre2182Mds0TgMyh6cre2182MdsNox4tm11Jusa
• decreased response of heart to induced stress_Nox4<tm1.1Jusa>/Nox4<tm1.1Jusa>,Tg(Myh6-cre)2182Mds/0
  http://metadb.riken.jp/0004486IC57BL6FVBNox4tm11JusaNox4tm11JusaTgMyh6cre2182Mds0TgMyh6cre2182MdsNox4tm11Jusa
• increased cardiomyocyte apoptosis_Tg(Myh6-Nox4)#Jusa/0
  http://metadb.riken.jp/0003222FVBTgMyh6Nox4JusaTgMyh6Nox4Jusa0TgMyh6Nox4Jusa