Hyun-Seok. Kim, et.al., Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis., Cell metabolism, 2010, 12

http://rdf.ncbi.nlm.nih.gov/pubmed/20816089

Hyun-Seok. Kim, et.al., Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis., Cell metabolism, 2010, 12

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Sirt6<tm1.1Cxd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4847905

class

http://purl.org/net/cito/citesAsAuthority

• Sirt6<tm1.1Cxd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4847905

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal liver morphology_Sirt6<tm1.1Cxd>/Sirt6<tm1.1Cxd>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0000598I129S6SvEvTacFVBNSirt6tm11CxdSirt6tm11CxdTgAlb1cre1Dlr0Sirt6tm11CxdTgAlb1cre1Dlr
• hepatic steatosis_Sirt6<tm1.1Cxd>/Sirt6<tm1.1Cxd>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0002628I129S6SvEvTacFVBNSirt6tm11CxdSirt6tm11CxdTgAlb1cre1Dlr0Sirt6tm11CxdTgAlb1cre1Dlr
• increased liver weight_Sirt6<tm1.1Cxd>/Sirt6<tm1.1Cxd>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0002981I129S6SvEvTacFVBNSirt6tm11CxdSirt6tm11CxdTgAlb1cre1Dlr0Sirt6tm11CxdTgAlb1cre1Dlr
• increased circulating glucose level_Sirt6<tm1.1Cxd>/Sirt6<tm1.1Cxd>,Tg(Alb1-cre)1Dlr/0
  http://metadb.riken.jp/0005559I129S6SvEvTacFVBNSirt6tm11CxdSirt6tm11CxdTgAlb1cre1Dlr0Sirt6tm11CxdTgAlb1cre1Dlr

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD24116
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD24116