Linyuan. Wang, et.al., Deletion of Pten in pancreatic ß-cells protects against deficient ß-cell mass and function in mouse models of type 2 diabetes., Diabetes, 2010, 59

http://rdf.ncbi.nlm.nih.gov/pubmed/20852026

Linyuan. Wang, et.al., Deletion of Pten in pancreatic ß-cells protects against deficient ß-cell mass and function in mouse models of type 2 diabetes., Diabetes, 2010, 59

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• insulin resistance_Lepr<db>/Lepr<db>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005331I129S4SvJaeC57BL6C57BLKSJDBALeprdbLeprdbPtentm1HwuPtentm1HwuTgIns2cre25Mgn0Ptentm1HwuTgIns2cre25MgnLeprdb
• abnormal pancreatic beta cell morphology_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005217I129S4SvJaeC57BL6DBAPtentm1HwuPtentm1HwuTgIns2cre25Mgn0TgIns2cre25MgnPtentm1Hwu
• increased pancreatic beta cell mass_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009113I129S4SvJaeC57BL6DBAPtentm1HwuPtentm1HwuTgIns2cre25Mgn0TgIns2cre25MgnPtentm1Hwu
• increased insulin secretion_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003058I129S4SvJaeC57BL6DBAPtentm1HwuPtentm1HwuTgIns2cre25Mgn0TgIns2cre25MgnPtentm1Hwu
• increased body weight_Lepr<db>/Lepr<db>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001260I129S4SvJaeC57BL6C57BLKSJDBALeprdbLeprdbPtentm1HwuPtentm1HwuTgIns2cre25Mgn0Ptentm1HwuTgIns2cre25MgnLeprdb
• improved glucose tolerance_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005292I129S4SvJaeC57BL6DBAPtentm1HwuPtentm1HwuTgIns2cre25Mgn0TgIns2cre25MgnPtentm1Hwu
• increased body weight_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001260I129S4SvJaeC57BL6DBAPtentm1HwuPtentm1HwuTgIns2cre25Mgn0TgIns2cre25MgnPtentm1Hwu
• increased insulin secretion_Lepr<db>/Lepr<db>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003058I129S4SvJaeC57BL6C57BLKSJDBALeprdbLeprdbPtentm1HwuPtentm1HwuTgIns2cre25Mgn0Ptentm1HwuTgIns2cre25MgnLeprdb
• increased insulin sensitivity_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0002891I129S4SvJaeC57BL6DBAPtentm1HwuPtentm1HwuTgIns2cre25Mgn0TgIns2cre25MgnPtentm1Hwu
• abnormal pancreatic islet morphology_Lepr<db>/Lepr<db>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005215I129S4SvJaeC57BL6C57BLKSJDBALeprdbLeprdbPtentm1HwuPtentm1HwuTgIns2cre25Mgn0Ptentm1HwuTgIns2cre25MgnLeprdb