Ling-Hui. Zeng, et.al., Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex., Human molecular genetics, 2011, 20

http://rdf.ncbi.nlm.nih.gov/pubmed/21062901

Ling-Hui. Zeng, et.al., Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex., Human molecular genetics, 2011, 20

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased brain size_Tg(GFAP-cre)8Gtm/0,Tsc2<tm1.1Mjg>/Tsc2<tm1.1Mjg>
  http://metadb.riken.jp/0005238I129X1SvJ129S1SvC57BL6CBATgGFAPcre8Gtm0Tsc2tm11MjgTsc2tm11MjgTgGFAPcre8GtmTsc2tm11Mjg
• abnormal hippocampus pyramidal cell morphology_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(GFAP-cre)8Gtm/0
  http://metadb.riken.jp/0009940I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm1DjkTgGFAPcre8Gtm0TgGFAPcre8GtmTsc1tm1Djk
• increased brain size_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(GFAP-cre)8Gtm/0
  http://metadb.riken.jp/0005238I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm1DjkTgGFAPcre8Gtm0TgGFAPcre8GtmTsc1tm1Djk
• seizures_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(GFAP-cre)8Gtm/0
  http://metadb.riken.jp/0002064I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm1DjkTgGFAPcre8Gtm0TgGFAPcre8GtmTsc1tm1Djk
• slow postnatal weight gain_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(GFAP-cre)8Gtm/0
  http://metadb.riken.jp/0008489I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm1DjkTgGFAPcre8Gtm0TgGFAPcre8GtmTsc1tm1Djk
• slow postnatal weight gain_Tg(GFAP-cre)8Gtm/0,Tsc2<tm1.1Mjg>/Tsc2<tm1.1Mjg>
  http://metadb.riken.jp/0008489I129X1SvJ129S1SvC57BL6CBATgGFAPcre8Gtm0Tsc2tm11MjgTsc2tm11MjgTgGFAPcre8GtmTsc2tm11Mjg
• premature death_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(GFAP-cre)8Gtm/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm1DjkTgGFAPcre8Gtm0TgGFAPcre8GtmTsc1tm1Djk
• seizures_Tg(GFAP-cre)8Gtm/0,Tsc2<tm1.1Mjg>/Tsc2<tm1.1Mjg>
  http://metadb.riken.jp/0002064I129X1SvJ129S1SvC57BL6CBATgGFAPcre8Gtm0Tsc2tm11MjgTsc2tm11MjgTgGFAPcre8GtmTsc2tm11Mjg
• premature death_Tg(GFAP-cre)8Gtm/0,Tsc2<tm1.1Mjg>/Tsc2<tm1.1Mjg>
  http://metadb.riken.jp/0002083I129X1SvJ129S1SvC57BL6CBATgGFAPcre8Gtm0Tsc2tm11MjgTsc2tm11MjgTgGFAPcre8GtmTsc2tm11Mjg
• increased brain weight_Tg(GFAP-cre)8Gtm/0,Tsc2<tm1.1Mjg>/Tsc2<tm1.1Mjg>
  http://metadb.riken.jp/0002176I129X1SvJ129S1SvC57BL6CBATgGFAPcre8Gtm0Tsc2tm11MjgTsc2tm11MjgTgGFAPcre8GtmTsc2tm11Mjg
• astrocytosis_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(GFAP-cre)8Gtm/0
  http://metadb.riken.jp/0003354I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm1DjkTgGFAPcre8Gtm0TgGFAPcre8GtmTsc1tm1Djk
• increased brain weight_Tsc1<tm1Djk>/Tsc1<tm1Djk>,Tg(GFAP-cre)8Gtm/0
  http://metadb.riken.jp/0002176I129S4SvJaeC57BL6CBATsc1tm1DjkTsc1tm1DjkTgGFAPcre8Gtm0TgGFAPcre8GtmTsc1tm1Djk
• astrocytosis_Tg(GFAP-cre)8Gtm/0,Tsc2<tm1.1Mjg>/Tsc2<tm1.1Mjg>
  http://metadb.riken.jp/0003354I129X1SvJ129S1SvC57BL6CBATgGFAPcre8Gtm0Tsc2tm11MjgTsc2tm11MjgTgGFAPcre8GtmTsc2tm11Mjg
• abnormal hippocampus pyramidal cell morphology_Tg(GFAP-cre)8Gtm/0,Tsc2<tm1.1Mjg>/Tsc2<tm1.1Mjg>
  http://metadb.riken.jp/0009940I129X1SvJ129S1SvC57BL6CBATgGFAPcre8Gtm0Tsc2tm11MjgTsc2tm11MjgTgGFAPcre8GtmTsc2tm11Mjg

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD43974
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD43974
• CD41689
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD41689