Charlly. Kao, et.al., Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection., Nature immunology, 2011, 12

http://rdf.ncbi.nlm.nih.gov/pubmed/21623380

Charlly. Kao, et.al., Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection., Nature immunology, 2011, 12

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased tumor necrosis factor secretion_Tbx21<tm2Srnr>/Tbx21<tm2Srnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008560I129C57BL6DBA2Tbx21tm2SrnrTbx21tm2SrnrTgCd4cre1Cwi0TgCd4cre1CwiTbx21tm2Srnr
• decreased CD8-positive, alpha-beta T cell number_Tbx21<tm2Srnr>/Tbx21<+>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008079I129C57BL6DBA2Tbx21tm2SrnrTbx21TgCd4cre1Cwi0Tbx21Tbx21tm2SrnrTgCd4cre1Cwi
• increased susceptibility to viral infection_Tbx21<tm2Srnr>/Tbx21<+>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0002418I129C57BL6DBA2Tbx21tm2SrnrTbx21TgCd4cre1Cwi0Tbx21Tbx21tm2SrnrTgCd4cre1Cwi
• increased interleukin-17 secretion_Tbx21<tm2Srnr>/Tbx21<tm2Srnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008681I129C57BL6DBA2Tbx21tm2SrnrTbx21tm2SrnrTgCd4cre1Cwi0TgCd4cre1CwiTbx21tm2Srnr
• decreased CD8-positive, alpha-beta T cell number_Tbx21<tm2Srnr>/Tbx21<tm2Srnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008079I129C57BL6DBA2Tbx21tm2SrnrTbx21tm2SrnrTgCd4cre1Cwi0TgCd4cre1CwiTbx21tm2Srnr
• increased susceptibility to viral infection_Tbx21<tm2Srnr>/Tbx21<tm2Srnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0002418I129C57BL6DBA2Tbx21tm2SrnrTbx21tm2SrnrTgCd4cre1Cwi0TgCd4cre1CwiTbx21tm2Srnr
• increased interleukin-2 secretion_Tbx21<tm2Srnr>/Tbx21<tm2Srnr>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008687I129C57BL6DBA2Tbx21tm2SrnrTbx21tm2SrnrTgCd4cre1Cwi0TgCd4cre1CwiTbx21tm2Srnr