Nobuhiko. Kayagaki, et.al., Non-canonical inflammasome activation targets caspase-11., Nature, 2011, 479

http://rdf.ncbi.nlm.nih.gov/pubmed/22002608

Nobuhiko. Kayagaki, et.al., Non-canonical inflammasome activation targets caspase-11., Nature, 2011, 479

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Casp4<del>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5473345
• Casp4<tm1.1Gne>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5468949
• Tg(Casp4)#Gne
  http://metadb.riken.jp/db/mgi_rdf/MGI:5468960

class

http://purl.org/net/cito/citesAsAuthority

• Casp4<del>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5473345
• Casp4<tm1.1Gne>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5468949
• Tg(Casp4)#Gne
  http://metadb.riken.jp/db/mgi_rdf/MGI:5468960

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating interleukin-1 beta level_Nlrp3<tm1Vmd>/Nlrp3<tm1Vmd>
  http://metadb.riken.jp/0008642B6B6NNlrp3tm1VmdNlrp3tm1VmdNlrp3tm1VmdNlrp3tm1Vmd
• decreased circulating interleukin-18 level_Casp4<tm1.1Gne>/Casp4<tm1.1Gne>
  http://metadb.riken.jp/0008636IC57BL6Casp4tm11GneCasp4tm11GneCasp4tm11Gne
• decreased macrophage apoptosis_Casp4<tm1.1Gne>/Casp4<tm1.1Gne>
  http://metadb.riken.jp/0011081IC57BL6Casp4tm11GneCasp4tm11GneCasp4tm11Gne
• decreased macrophage apoptosis_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>,Tg(Casp4)#Gne/0
  http://metadb.riken.jp/0011081I129S2SvPasC57BL6NODShiLtJCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delTgCasp4Gne0TgCasp4GneCasp1tm1SeshCasp4del
• decreased interleukin-1 beta secretion_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>,Tg(Casp4)#Gne/0
  http://metadb.riken.jp/0008658I129S2SvPasC57BL6NODShiLtJCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delTgCasp4Gne0TgCasp4GneCasp1tm1SeshCasp4del
• decreased circulating interleukin-18 level_Pycard<tm1Vmd>/Pycard<tm1Vmd>
  http://metadb.riken.jp/0008636B6129Pycardtm1VmdPycardtm1VmdPycardtm1VmdPycardtm1Vmd
• decreased susceptibility to endotoxin shock_Casp4<tm1.1Gne>/Casp4<tm1.1Gne>
  http://metadb.riken.jp/0008734IC57BL6Casp4tm11GneCasp4tm11GneCasp4tm11Gne
• decreased circulating interleukin-18 level_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>,Tg(Casp4)#Gne/0
  http://metadb.riken.jp/0008636I129S2SvPasC57BL6NODShiLtJCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delTgCasp4Gne0TgCasp4GneCasp1tm1SeshCasp4del
• decreased susceptibility to endotoxin shock_Nlrp3<tm1Vmd>/Nlrp3<tm1Vmd>
  http://metadb.riken.jp/0008734B6B6NNlrp3tm1VmdNlrp3tm1VmdNlrp3tm1VmdNlrp3tm1Vmd
• decreased interleukin-18 secretion_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>,Tg(Casp4)#Gne/0
  http://metadb.riken.jp/0008685I129S2SvPasC57BL6NODShiLtJCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delTgCasp4Gne0TgCasp4GneCasp1tm1SeshCasp4del
• decreased circulating interleukin-18 level_Nlrp3<tm1Vmd>/Nlrp3<tm1Vmd>
  http://metadb.riken.jp/0008636B6B6NNlrp3tm1VmdNlrp3tm1VmdNlrp3tm1VmdNlrp3tm1Vmd
• decreased circulating interleukin-1 beta level_Casp4<tm1.1Gne>/Casp4<tm1.1Gne>
  http://metadb.riken.jp/0008642IC57BL6Casp4tm11GneCasp4tm11GneCasp4tm11Gne
• decreased circulating interleukin-1 alpha level_Casp4<tm1.1Gne>/Casp4<tm1.1Gne>
  http://metadb.riken.jp/0008639IC57BL6Casp4tm11GneCasp4tm11GneCasp4tm11Gne
• decreased circulating interleukin-1 beta level_Pycard<tm1Vmd>/Pycard<tm1Vmd>
  http://metadb.riken.jp/0008642B6129Pycardtm1VmdPycardtm1VmdPycardtm1VmdPycardtm1Vmd
• decreased interleukin-1 beta secretion_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>
  http://metadb.riken.jp/0008658B6129S2NODCasp1tm1SeshCasp4delCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delCasp4delCasp1tm1Sesh
• decreased interleukin-1 alpha secretion_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>
  http://metadb.riken.jp/0008655B6129S2NODCasp1tm1SeshCasp4delCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delCasp4delCasp1tm1Sesh
• decreased susceptibility to endotoxin shock_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>,Tg(Casp4)#Gne/0
  http://metadb.riken.jp/0008734I129S2SvPasC57BL6NODShiLtJCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delTgCasp4Gne0TgCasp4GneCasp1tm1SeshCasp4del
• decreased interleukin-1 beta secretion_Casp4<tm1.1Gne>/Casp4<tm1.1Gne>
  http://metadb.riken.jp/0008658IC57BL6Casp4tm11GneCasp4tm11GneCasp4tm11Gne
• decreased interleukin-1 alpha secretion_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>,Tg(Casp4)#Gne/0
  http://metadb.riken.jp/0008655I129S2SvPasC57BL6NODShiLtJCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delTgCasp4Gne0TgCasp4GneCasp1tm1SeshCasp4del
• decreased circulating interleukin-1 beta level_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>,Tg(Casp4)#Gne/0
  http://metadb.riken.jp/0008642I129S2SvPasC57BL6NODShiLtJCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delTgCasp4Gne0TgCasp4GneCasp1tm1SeshCasp4del
• decreased susceptibility to endotoxin shock_Pycard<tm1Vmd>/Pycard<tm1Vmd>
  http://metadb.riken.jp/0008734B6129Pycardtm1VmdPycardtm1VmdPycardtm1VmdPycardtm1Vmd
• decreased circulating interleukin-1 alpha level_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>
  http://metadb.riken.jp/0008639B6129S2NODCasp1tm1SeshCasp4delCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delCasp4delCasp1tm1Sesh
• decreased interleukin-1 beta secretion_Nlrp3<tm1Vmd>/Nlrp3<tm1Vmd>
  http://metadb.riken.jp/0008658B6B6NNlrp3tm1VmdNlrp3tm1VmdNlrp3tm1VmdNlrp3tm1Vmd
• decreased susceptibility to endotoxin shock_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>
  http://metadb.riken.jp/0008734B6129S2NODCasp1tm1SeshCasp4delCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delCasp4delCasp1tm1Sesh
• decreased sensitivity to xenobiotic induced morbidity/mortality_Casp4<tm1.1Gne>/Casp4<tm1.1Gne>
  http://metadb.riken.jp/0009767IC57BL6Casp4tm11GneCasp4tm11GneCasp4tm11Gne
• decreased macrophage apoptosis_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>
  http://metadb.riken.jp/0011081B6129S2NODCasp1tm1SeshCasp4delCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delCasp4delCasp1tm1Sesh
• decreased circulating interleukin-1 beta level_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>
  http://metadb.riken.jp/0008642B6129S2NODCasp1tm1SeshCasp4delCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delCasp4delCasp1tm1Sesh
• decreased interleukin-18 secretion_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>
  http://metadb.riken.jp/0008685B6129S2NODCasp1tm1SeshCasp4delCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delCasp4delCasp1tm1Sesh
• decreased interleukin-1 beta secretion_Pycard<tm1Vmd>/Pycard<tm1Vmd>
  http://metadb.riken.jp/0008658B6129Pycardtm1VmdPycardtm1VmdPycardtm1VmdPycardtm1Vmd
• decreased sensitivity to xenobiotic induced morbidity/mortality_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>
  http://metadb.riken.jp/0009767B6129S2NODCasp1tm1SeshCasp4delCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delCasp4delCasp1tm1Sesh
• decreased interleukin-1 alpha secretion_Casp4<tm1.1Gne>/Casp4<tm1.1Gne>
  http://metadb.riken.jp/0008655IC57BL6Casp4tm11GneCasp4tm11GneCasp4tm11Gne
• decreased circulating interleukin-18 level_Casp1<tm1Sesh>/Casp1<tm1Sesh>,Casp4<del>/Casp4<del>
  http://metadb.riken.jp/0008636B6129S2NODCasp1tm1SeshCasp4delCasp1tm1SeshCasp1tm1SeshCasp4delCasp4delCasp4delCasp1tm1Sesh