Freddy D. Jeanneteau, et.al., BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

http://rdf.ncbi.nlm.nih.gov/pubmed/22232675

Freddy D. Jeanneteau, et.al., BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nr3c1<tm1.1Mvc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5306342

class

http://purl.org/net/cito/citesAsAuthority

• Nr3c1<tm1.1Mvc>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5306342

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased circulating corticosterone level_Nr3c1<tm1.1Mvc>/Nr3c1<+>,Tg(Sim1-cre)1Lowl/0
  http://metadb.riken.jp/0001745I129C57BL6FVBNr3c1tm11MvcNr3c1TgSim1cre1Lowl0Nr3c1tm11MvcNr3c1TgSim1cre1Lowl
• abnormal hypothalamus physiology_Col1a1<tm8(CAG-BDNF)Jae>/Col1a1<tm8(CAG-BDNF)Jae>,Tg(Sim1-cre)1Lowl/0
  http://metadb.riken.jp/0005645I129S4SvJaeC57BL6FVBCol1a1tm8CAGBDNFJaeCol1a1tm8CAGBDNFJaeTgSim1cre1Lowl0TgSim1cre1LowlCol1a1tm8CAGBDNFJae
• lethality, complete penetrance_Nr3c1<tm1.1Mvc>/Nr3c1<tm1.1Mvc>,Tg(Sim1-cre)1Lowl/0
  http://metadb.riken.jp/0011400I129C57BL6FVBNr3c1tm11MvcNr3c1tm11MvcTgSim1cre1Lowl0Nr3c1tm11MvcTgSim1cre1Lowl
• abnormal circulating corticosterone level_Ntrk2<tm1Rohr>/Ntrk2<+>
  http://metadb.riken.jp/0005345NSNtrk2tm1RohrNtrk2Ntrk2tm1RohrNtrk2
• decreased circulating adrenocorticotropin level_Ntrk2<tm1Rohr>/Ntrk2<+>
  http://metadb.riken.jp/0002664NSNtrk2tm1RohrNtrk2Ntrk2tm1RohrNtrk2
• abnormal hypothalamus physiology_Nr3c1<tm1.1Mvc>/Nr3c1<+>,Tg(Sim1-cre)1Lowl/0
  http://metadb.riken.jp/0005645I129C57BL6FVBNr3c1tm11MvcNr3c1TgSim1cre1Lowl0Nr3c1tm11MvcNr3c1TgSim1cre1Lowl
• decreased body weight_Nr3c1<tm1.1Mvc>/Nr3c1<+>,Tg(Sim1-cre)1Lowl/0
  http://metadb.riken.jp/0001262I129C57BL6FVBNr3c1tm11MvcNr3c1TgSim1cre1Lowl0Nr3c1tm11MvcNr3c1TgSim1cre1Lowl
• increased circulating adrenocorticotropin level_Nr3c1<tm1.1Mvc>/Nr3c1<+>,Tg(Sim1-cre)1Lowl/0
  http://metadb.riken.jp/0001748I129C57BL6FVBNr3c1tm11MvcNr3c1TgSim1cre1Lowl0Nr3c1tm11MvcNr3c1TgSim1cre1Lowl
• decreased circulating corticosterone level_Ntrk2<tm1Rohr>/Ntrk2<+>
  http://metadb.riken.jp/0002665NSNtrk2tm1RohrNtrk2Ntrk2tm1RohrNtrk2